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BCAN
Gene Name
brevican
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Proteinaceous Extracellular Matrix
Golgi Lumen
Anchored Component Of Membrane
Lysosomal Lumen
Molecular Function
Extracellular Matrix Structural Constituent
Hyaluronic Acid Binding
Carbohydrate Binding
Biological Process
Skeletal System Development
Carbohydrate Metabolic Process
Cell Adhesion
Central Nervous System Development
Pathogenesis
Hippocampus Development
Extracellular Matrix Disassembly
Extracellular Matrix Organization
Glycosaminoglycan Metabolic Process
Chondroitin Sulfate Metabolic Process
Chondroitin Sulfate Biosynthetic Process
Chondroitin Sulfate Catabolic Process
Dermatan Sulfate Biosynthetic Process
Small Molecule Metabolic Process
Pathways
MPS IIIB - Sanfilippo syndrome B
Diseases of glycosylation
Heparan sulfate/heparin (HS-GAG) metabolism
Defective B4GALT7 causes EDS, progeroid type
MPS I - Hurler syndrome
MPS IX - Natowicz syndrome
Chondroitin sulfate/dermatan sulfate metabolism
CS/DS degradation
Defective SLC26A2 causes chondrodysplasias
Glycosaminoglycan metabolism
Degradation of the extracellular matrix
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
Defective CHST14 causes EDS, musculocontractural type
Defective PAPSS2 causes SEMD-PA
MPS IIIA - Sanfilippo syndrome A
Myoclonic epilepsy of Lafora
ECM proteoglycans
Defective CHST6 causes MCDC1
Glycogen storage diseases
MPS IIID - Sanfilippo syndrome D
A tetrasaccharide linker sequence is required for GAG synthesis
Chondroitin sulfate biosynthesis
MPS IIIC - Sanfilippo syndrome C
Diseases associated with glycosaminoglycan metabolism
Mucopolysaccharidoses
Defective EXT2 causes exostoses 2
MPS II - Hunter syndrome
Defective B3GAT3 causes JDSSDHD
Defective CHST3 causes SEDCJD
Defective EXT1 causes exostoses 1, TRPS2 and CHDS
MPS IV - Morquio syndrome A
Dermatan sulfate biosynthesis
MPS IV - Morquio syndrome B
Defective CHSY1 causes TPBS
MPS VII - Sly syndrome
Metabolism of carbohydrates
MPS VI - Maroteaux-Lamy syndrome
Drugs
Diseases
GWAS
Protein-protein Interactions
10 interactors:
ADAMTS4
FBLN2
MMP1
MMP10
MMP13
MMP2
MMP3
MMP7
MMP8
TNR
Entrez ID
63827
HPRD ID
02644
Ensembl ID
ENSG00000132692
Uniprot IDs
Q96GW7
PDB IDs
Enriched GO Terms of Interacting Partners
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Extracellular Matrix Organization
Extracellular Structure Organization
Extracellular Matrix Disassembly
Collagen Catabolic Process
Collagen Metabolic Process
Multicellular Organismal Macromolecule Metabolic Process
Multicellular Organismal Metabolic Process
Proteolysis
Catabolic Process
Positive Regulation Of Protein Oligomerization
Regulation Of Protein Oligomerization
Endodermal Cell Differentiation
Endoderm Formation
Protein Metabolic Process
Cellular Response To Amino Acid Stimulus
Antibacterial Peptide Secretion
Antibacterial Peptide Biosynthetic Process
Negative Regulation Of Axon Extension Involved In Regeneration
Endoderm Development
Response To Amino Acid
Formation Of Primary Germ Layer
Skeletal System Development
Negative Regulation Of Hydrogen Peroxide Metabolic Process
Positive Regulation Of Protein Complex Assembly
Cellular Response To Acid Chemical
Gastrulation
Defense Response To Bacterium
Positive Regulation Of Transmission Of Nerve Impulse
Negative Regulation Of Axon Regeneration
Positive Regulation Of Oxidative Stress-induced Cell Death
Intramembranous Ossification
Regulation Of Hydrogen Peroxide Metabolic Process
Bone Trabecula Formation
Response To External Stimulus
Regulation Of Transmission Of Nerve Impulse
Locomotory Exploration Behavior
Blood Vessel Maturation
Skeletal System Morphogenesis
Cellular Response To Nitric Oxide
Ossification
Neuron Cell-cell Adhesion
Response To Nitric Oxide
Positive Regulation Of Cellular Component Biogenesis
Bone Trabecula Morphogenesis
Regulation Of Axon Regeneration
Regulation Of Protein Complex Assembly
Growth Plate Cartilage Development
Response To Stress
Positive Regulation Of Synaptic Transmission, Glutamatergic
Cellular Response To Reactive Nitrogen Species
Tagcloud
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abundant
astrocytes
basic
cg
clustering
differentiated
diverse
embryos
enriched
fbln2
forebrain
foundation
functionally
glial
itih3
mesenchymal
ncam1
nervous
networks
neural
nsc
nscs
ontology
regulators
rich
tnr
transcriptomes
vcan
wnt