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SAA1
Description
serum amyloid A1
Image
GO Annotations
Cellular Component
Extracellular Region
Cytoplasmic Microtubule
High-density Lipoprotein Particle
Extracellular Exosome
Endocytic Vesicle Lumen
Molecular Function
G Protein-coupled Receptor Binding
Heparin Binding
Biological Process
Positive Regulation Of Cytokine Production
Acute-phase Response
Positive Regulation Of Cytosolic Calcium Ion Concentration
Platelet Activation
Neutrophil Chemotaxis
Positive Regulation Of Interleukin-1 Production
Positive Regulation Of Cell Adhesion
Macrophage Chemotaxis
Lymphocyte Chemotaxis
Regulation Of Protein Secretion
Negative Regulation Of Inflammatory Response
Pathways
Scavenging by Class B Receptors
G alpha (q) signalling events
G alpha (i) signalling events
Formyl peptide receptors bind formyl peptides and many other ligands
TAK1-dependent IKK and NF-kappa-B activation
Interleukin-4 and Interleukin-13 signaling
Advanced glycosylation endproduct receptor signaling
Advanced glycosylation endproduct receptor signaling
TRAF6 mediated NF-kB activation
Amyloid fiber formation
Drugs
Diseases
GWAS
Amyloid A serum levels (
21124955
)
Blood protein levels (
30072576
)
Rosacea symptom severity (
29771307
)
Novel Interacting Genes
1 novel interacting genes:
GNG5
Interacting Genes
9 interacting genes:
COL4A1
COL4A2
COL4A3
COL4A4
FPR1
GLP1R
LAMA1
SELENOS
VKORC1
Entrez ID
6288
HPRD ID
00097
Ensembl ID
ENSG00000173432
Uniprot IDs
P0DJI8
PDB IDs
4IP8
4IP9
6MST
7ZKY
Enriched GO Terms of Interacting Partners
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Collagen Type IV Trimer
Basement Membrane
Extracellular Matrix Structural Constituent
Extracellular Matrix Structural Constituent Conferring Tensile Strength
Collagen-activated Tyrosine Kinase Receptor Signaling Pathway
Collagen-activated Signaling Pathway
Collagen Trimer
Endoplasmic Reticulum Lumen
Extracellular Matrix
Retinal Blood Vessel Morphogenesis
Extracellular Structure Organization
Extracellular Matrix Organization
Retina Vasculature Morphogenesis In Camera-type Eye
Glomerular Basement Membrane Development
Cell Surface Receptor Signaling Pathway
Signal Transduction
Glucagon-like Peptide 1 Receptor Activity
Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity
N-formyl Peptide Receptor Activity
Derlin-1-VIMP Complex
Peptidyl-glutamic Acid Carboxylation
Oxidoreductase Activity, Acting On CH Or CH2 Groups, Disulfide As Acceptor
Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity
Blood Vessel Morphogenesis
Glucagon Receptor Activity
Laminin-1 Complex
Laminin-3 Complex
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Scavenger Receptor Binding
Laminin Complex
Branching Morphogenesis Of An Epithelial Tube
Negative Regulation Of Angiogenesis
Negative Regulation Of Vasculature Development
Regulation Of Multicellular Organismal Process
Response To Psychosocial Stress
Morphogenesis Of A Branching Epithelium
Positive Regulation Of Cytosolic Calcium Ion Concentration
Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus
Glycosphingolipid Binding
Morphogenesis Of A Branching Structure
Extracellular Region
Negative Regulation Of Macrophage Apoptotic Process
Complement Receptor Activity
Cellular Response To Peptide Hormone Stimulus
Post-translational Protein Targeting To Membrane, Translocation
Derlin-1 Retrotranslocation Complex
Regulation Of Basement Membrane Organization
Molecular Adaptor Activity
Negative Regulation Of Glycogen Biosynthetic Process
Protein Complex Involved In Cell-matrix Adhesion
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