PVRL1

Gene Name		poliovirus receptor-related 1 (herpesvirus entry mediator C)
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Gene Ontology Annotations	Cellular Component	Extracellular Region Plasma Membrane Adherens Junction Cell-cell Adherens Junction Membrane Integral Component Of Membrane Catenin Complex Axon Growth Cone Membrane Presynaptic Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Virus Receptor Activity Protein Binding Coreceptor Activity Carbohydrate Binding Protein Homodimerization Activity Virion Binding Protein Heterodimerization Activity Cell Adhesion Molecule Binding
	Biological Process	Lens Morphogenesis In Camera-type Eye Desmosome Organization Iron Ion Transport Immune Response Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Signal Transduction Axon Guidance Response To Virus Single Organismal Cell-cell Adhesion Cell Junction Assembly Adherens Junction Organization Cell-cell Junction Organization Viral Entry Into Host Cell Regulation Of Synapse Assembly Retina Development In Camera-type Eye Enamel Mineralization
Pathways		Nectin/Necl trans heterodimerization Cell junction organization Cell-cell junction organization Adherens junctions interactions
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: MLLT4 PARD3 PRNP PVR PVRL3 PVRL4
Entrez ID		5818
HPRD ID		07200
Ensembl ID		ENSG00000110400
Uniprot IDs		Q15223
PDB IDs		3ALP 3SKU 3U82 3U83 4FMF
Enriched GO Terms of Interacting Partners?		Cell Junction Assembly Cell-cell Junction Organization Adherens Junction Organization Cellular Component Assembly Cell Adhesion Susceptibility To T Cell Mediated Cytotoxicity Negative Regulation Of Calcineurin-NFAT Signaling Cascade Epithelial Cell Development Susceptibility To Natural Killer Cell Mediated Cytotoxicity Cellular Response To Copper Ion Apical Constriction Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Establishment Of Endothelial Intestinal Barrier Asymmetric Cell Division Negative Regulation Of Calcium-mediated Signaling Positive Regulation Of Immune Response To Tumor Cell Negative Regulation Of Interleukin-17 Production Regulation Of Calcineurin-NFAT Signaling Cascade Negative Regulation Of Protein Phosphorylation Locomotion Positive Regulation Of Myelination Negative Regulation Of Activated T Cell Proliferation Negative Regulation Of Phosphorylation Positive Regulation Of Rap GTPase Activity Movement Of Cell Or Subcellular Component Establishment Of Epithelial Cell Polarity Negative Regulation Of Interleukin-2 Production Negative Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Cellular Copper Ion Homeostasis Negative Regulation Of T Cell Receptor Signaling Pathway Positive Regulation Of Natural Killer Cell Mediated Immunity Response To Copper Ion Regulation Of Rap GTPase Activity Copper Ion Homeostasis Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Tissue Development Regulation Of Rap Protein Signal Transduction Single Organismal Cell-cell Adhesion Axonogenesis Establishment Of Endothelial Barrier Epithelial Cell Differentiation Lens Morphogenesis In Camera-type Eye Cell Development Viral Process Centrosome Localization Axon Development Cell Morphogenesis Involved In Neuron Differentiation Negative Regulation Of Interferon-gamma Production
Tagcloud ?		11q23 12q11 12q14 12q15 12q21 17q11 17q12 3p12 6p21 6q21 6q23 9p13 9p21 acc accs adenoid amplicons ccnd3 cnas cnot2 glipr1l1 mec mecs mucoepidermoid numa1 pax5 rab3ip sdc statuses