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NECTIN1
Description
nectin cell adhesion molecule 1
Image
GO Annotations
Cellular Component
Extracellular Region
Plasma Membrane
Adherens Junction
Membrane
Axon
Dendrite
Growth Cone Membrane
Presynaptic Membrane
Cell Projection
Apical Junction Complex
Cell-cell Contact Zone
Synapse
Presynaptic Active Zone Membrane
Anchoring Junction
Hippocampal Mossy Fiber To CA3 Synapse
Molecular Function
Virus Receptor Activity
Protein Binding
Coreceptor Activity
Carbohydrate Binding
Signaling Receptor Activity
Identical Protein Binding
Protein Homodimerization Activity
Protein-containing Complex Binding
Virion Binding
Cell Adhesion Molecule Binding
Cell Adhesion Mediator Activity
Biological Process
Lens Morphogenesis In Camera-type Eye
Desmosome Organization
Iron Ion Transport
Immune Response
Cell Adhesion
Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Axon Guidance
Symbiont Entry Into Host Cell
Camera-type Eye Morphogenesis
Regulation Of Synapse Organization
Regulation Of Synapse Assembly
Retina Development In Camera-type Eye
Enamel Mineralization
Cochlea Morphogenesis
Cell-cell Adhesion
Protein Localization To Cell Junction
Pathways
Adherens junctions interactions
Nectin/Necl trans heterodimerization
Drugs
Diseases
Isolated orofacial clefts, including: Cleft lip with or without cleft palate; Cleft palate
GWAS
Interacting Genes
10 interacting genes:
AFDN
CBL
FGFR1
FGFR2
FGFR3
NECTIN3
NECTIN4
PARD3
PRNP
PVR
Entrez ID
5818
HPRD ID
07200
Ensembl ID
ENSG00000110400
Uniprot IDs
Q15223
PDB IDs
3ALP
3SKU
3U82
3U83
4FMF
4MYW
Enriched GO Terms of Interacting Partners
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Positive Regulation Of Phospholipase Activity
Fibroblast Growth Factor Receptor Activity
Positive Regulation Of Lipase Activity
Cell Adhesion Mediator Activity
Adherens Junction
Fibroblast Growth Factor Binding
Fibroblast Growth Factor Receptor Signaling Pathway Involved In Orbitofrontal Cortex Development
Symbiont Entry Into Host Cell
Ventricular Zone Neuroblast Division
Orbitofrontal Cortex Development
Biological Process Involved In Interaction With Host
Plasma Membrane
Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Transmembrane Receptor Protein Tyrosine Kinase Activity
Forebrain Neuroblast Division
Forebrain Ventricular Zone Progenitor Cell Division
Fibroblast Growth Factor Receptor Signaling Pathway
Lung-associated Mesenchyme Development
Endochondral Bone Growth
Biomineral Tissue Development
Cell Adhesion Molecule Binding
Branching Involved In Salivary Gland Morphogenesis
Signal Transduction
Positive Regulation Of Hydrolase Activity
Bone Growth
Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Protein Tyrosine Kinase Activity
Anchoring Junction
Regulation Of Postsynapse Organization
Cell Adhesion
Mesenchymal Cell Proliferation
Cell-cell Contact Zone
Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity
Positive Regulation Of Mesenchymal Cell Proliferation
Positive Regulation Of Cardiac Muscle Cell Proliferation
Gland Morphogenesis
Apical Junction Complex
Cell-cell Adhesion
Cellular Response To Fibroblast Growth Factor Stimulus
Midbrain Development
Receptor Complex
Identical Protein Binding
Regulation Of Mesenchymal Cell Proliferation
Bone Morphogenesis
Cell-cell Junction
Positive Regulation Of Heart Growth
Establishment Of Protein Localization To Membrane
Tight Junction
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules
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