PAF1

Gene Name		Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
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Gene Ontology Annotations	Cellular Component	Cdc73/Paf1 Complex
	Molecular Function	RNA Polymerase II Core Binding Chromatin Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Endodermal Cell Fate Commitment Transcription, DNA-templated MRNA Polyadenylation Histone Monoubiquitination Wnt Signaling Pathway Stem Cell Maintenance Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Histone H2B Ubiquitination Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Lipopolysaccharide
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		12 interactors: FXR2 HIST1H1C HIST1H3A KAT8 KMT2A LEO1 MLLT1 MSL1 MSL2 MSL3 RNF20 TCEA1
Entrez ID		54623
HPRD ID		10140
Ensembl ID		ENSG00000006712
Uniprot IDs		M0QX35 Q8N7H5
PDB IDs		4M6T
Enriched GO Terms of Interacting Partners?		Histone H4-K16 Acetylation Chromatin Organization Histone H4 Acetylation Chromosome Organization Histone Modification Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Chromatin Modification Peptidyl-lysine Modification Organelle Organization Histone H2B Ubiquitination Histone Monoubiquitination Peptidyl-amino Acid Modification Regulation Of Gene Expression Histone Ubiquitination Positive Regulation Of Histone Methylation Protein Monoubiquitination Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription, DNA-templated Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Histone Methylation Regulation Of DNA-templated Transcription, Elongation Cellular Protein Modification Process Regulation Of RNA Metabolic Process DNA Methylation Transcription, DNA-templated Positive Regulation Of Cellular Response To Drug Positive Regulation Of Macromolecule Biosynthetic Process Gene Expression RNA Biosynthetic Process Positive Regulation Of Histone Modification Positive Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process DNA Modification Regulation Of Histone H3-K14 Acetylation Regulation Of Cellular Response To Drug Protein Metabolic Process Nucleosome Assembly Regulation Of Histone Modification Chromatin Assembly Nucleosome Organization Regulation Of Metabolic Process Regulation Of Response To Drug
Tagcloud ?		ablates ada2 ap2 apicomplexa apicomplexan dd ddhagcn5b destabilization dispensable e703g gcn5a gcn5b gondii indispensable invertebrates kat kats leo1 lytic parasite parasites phylum possessing proteomics protozoan redundant rrm tfiid toxoplasma