PAF1

Description		PAF1 component of Paf1/RNA polymerase II complex
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GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Membrane Cdc73/Paf1 Complex
	Molecular Function	RNA Polymerase II Complex Binding Chromatin Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Endodermal Cell Fate Commitment Transcription Elongation By RNA Polymerase II Wnt Signaling Pathway Stem Cell Population Maintenance MRNA 3'-end Processing Protein Localization To Nucleus Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Lipopolysaccharide Positive Regulation Of Cell Cycle G1/S Phase Transition
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS
Novel Interacting Genes		2 novel interacting genes: EXOSC5 RERE
Interacting Genes		17 interacting genes: CEBPA ENO1 ERCC6 FXR2 H1-2 H3C1 HSPB1 KAT8 KMT2A MLLT1 MSL1 MSL2 MSL3 RNF20 SUMO2 TCEA1 TULP3
Entrez ID		54623
HPRD ID		10140
Ensembl ID		ENSG00000006712
Uniprot IDs		Q8N7H5
PDB IDs		4M6T 5ZYQ 6GMH 6TED 7OOP 7OPC 7OPD 7UNC 7UND 8A3Y 9EGX 9EGY 9EGZ 9EH0 9EH2
Enriched GO Terms of Interacting Partners?		MSL Complex Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of RNA Metabolic Process Regulation Of RNA Metabolic Process Chromatin Organization Nucleus Chromatin Remodeling Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Metabolic Process Nucleoplasm Chromatin Binding Epigenetic Regulation Of Gene Expression Positive Regulation Of DNA-templated Transcription Initiation Regulation Of DNA-templated Transcription Initiation DNA Binding Positive Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II Transcription Elongation Factor Complex Nucleolus NuA4 Histone Acetyltransferase Complex MLL1 Complex Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Chromosome Protein Homodimerization Activity RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Negative Regulation Of Protein Kinase C Signaling Histone H2B Ubiquitin Ligase Activity Histone H2B C-terminal K Residue Ubiquitin Ligase Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of Proteolysis Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Protein Metabolic Process DNA-templated Transcription Elongation Positive Regulation Of Gene Expression, Epigenetic Cerebellar Purkinje Cell Layer Maturation Response To Vitamin B2 C/EBP Complex
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