AFF1

Gene Name		AF4/FMR2 family, member 1
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Gene Ontology Annotations	Cellular Component	Transcription Elongation Factor Complex
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Bulimia nervosa ( 23568457) Systemic lupus erythematosus ( 22291604) Triglycerides ( 20864672 20686565)
Protein-protein Interactions		7 interactors: HIST3H3 MLLT1 MLLT3 NT5E SIAH1 SIAH2 SMAD9
Entrez ID		4299
HPRD ID		08871
Ensembl ID		ENSG00000172493
Uniprot IDs		P51825 Q14C88
PDB IDs		2LM0
Enriched GO Terms of Interacting Partners?		Adenosine Biosynthetic Process AMP Catabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Purine Nucleoside Monophosphate Catabolic Process Regulation Of Canonical Wnt Signaling Pathway Mullerian Duct Regression Cellular Metabolic Process Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Regulation Of Wnt Signaling Pathway Positive Regulation Of Non-canonical Wnt Signaling Pathway Purine Ribonucleoside Catabolic Process Nucleobase-containing Compound Metabolic Process AMP Metabolic Process Adenosine Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Segment Specification Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Axon Guidance Anatomical Structure Regression Pyrimidine Nucleoside Catabolic Process Cellular Nitrogen Compound Metabolic Process Protein Destabilization Purine Ribonucleotide Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Nitrogen Compound Metabolic Process
Tagcloud ?		abl1 cbfb cryptic cytogenetics dek ell etv6 fifteen inv mll mllt1 mllt10 mllt3 mllt4 mllt6 mrt multiplex myh11 nup214 p13 pbx1 q23 rara runx1 runx1t1 simplified tcf3 translocations zbtb16