LAIR1

Name	leukocyte associated immunoglobulin like receptor 1
Structure
Novel Interactors	8 novel interactors: CENPB CFL2 CNOT3 KIR3DS1 LAIR2 MYH3 PRKCG PTPRH
Interactors	5 interactors: APP COL1A1 CSK PTPN11 PTPN6
GO Annotations	Cellular Component	Plasma Membrane Membrane Specific Granule Membrane Tertiary Granule Membrane
	Molecular Function	Protein Binding
	Biological Process	Adaptive Immune Response Immune System Process Immune Response-regulating Signaling Pathway
Pathways	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Neutrophil degranulation
GWAS	No GWAS studies recorded
Entrez ID	3903
HPRD ID	04292
Ensembl ID	ENSG00000167613
Uniprot IDs	A0A0G2JMI0 A0A0G2JNK8 A0A140T8W3 A8MZ84 D3YTC8 Q6GTX8
PDB IDs	3KGR 3RP1 7F9L 7F9M 7F9N
GO Terms Enriched among Interactors ?	Face Morphogenesis T Cell Costimulation Negative Regulation Of Neutrophil Activation Myeloid Cell Development Regulation Of Immune Response Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Dephosphorylation Regulation Of Neutrophil Activation Neutrophil Activation Involved In Immune Response Regulation Of ERK1 And ERK2 Cascade Protein Tyrosine Phosphatase Activity Negative Regulation Of Cell Adhesion Transmembrane Receptor Protein Tyrosine Phosphatase Activity Insulin Receptor Binding Myeloid Leukocyte Activation Negative Regulation Of T Cell Activation Peptidyl-tyrosine Dephosphorylation Phosphoprotein Phosphatase Activity Platelet Formation Dephosphorylation Megakaryocyte Development Positive Regulation Of Cell Activation Regulation Of Interleukin-6 Production Immune Response-regulating Signaling Pathway Negative Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Lipopolysaccharide-mediated Signaling Pathway Neutrophil Activation Cell Activation Involved In Immune Response Negative Regulation Of T Cell Receptor Signaling Pathway Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Lymphocyte Activation Hemopoiesis Response To Mechanical Stimulus Sarcomere Organization Cell-cell Junction Protein Tyrosine Kinase Binding Negative Regulation Of Leukocyte Activation Negative Regulation Of Cell-cell Adhesion Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Type I Interferon-mediated Signaling Pathway Negative Regulation Of Protein Localization Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Immune System Process Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Leukocyte Activation Cellular Response To Epidermal Growth Factor Stimulus Cellular Response To Vitamin E