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KLK2
Gene Name
kallikrein-related peptidase 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Extracellular Vesicular Exosome
Molecular Function
Serine-type Endopeptidase Activity
Biological Process
Proteolysis
Extracellular Matrix Disassembly
Extracellular Matrix Organization
Pathways
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Activation of Matrix Metalloproteinases
Degradation of the extracellular matrix
Drugs
Diseases
GWAS
PCA3 expression level (
23555189
)
Prostate-specific antigen levels (
23359319
)
Protein-protein Interactions
14 interactors:
A2M
APP
AR
IGFBP2
POLR2A
SEMG1
SEMG2
SERPINA3
SERPINA4
SERPINA5
SERPINB6
SERPINC1
SERPINE1
SERPINF2
Entrez ID
3817
HPRD ID
01006
Ensembl ID
ENSG00000167751
Uniprot IDs
B4DU77
P20151
PDB IDs
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Endopeptidase Activity
Negative Regulation Of Peptidase Activity
Negative Regulation Of Proteolysis
Negative Regulation Of Protein Processing
Regulation Of Endopeptidase Activity
Negative Regulation Of Hydrolase Activity
Regulation Of Protein Processing
Regulation Of Peptidase Activity
Regulation Of Proteolysis
Negative Regulation Of Catalytic Activity
Negative Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Protein Metabolic Process
Platelet Degranulation
Blood Coagulation
Hemostasis
Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Body Fluid Levels
Regulation Of Protein Metabolic Process
Wound Healing
Regulation Of Catalytic Activity
Response To Wounding
Platelet Activation
Negative Regulation Of Plasminogen Activation
Negative Regulation Of Fibrinolysis
Regulation Of Fibrinolysis
Regulation Of Blood Coagulation
Exocytosis
Extracellular Matrix Organization
Extracellular Structure Organization
Regulation Of Wound Healing
Reproductive Process
Transcription Initiation From RNA Polymerase II Promoter
Fibrinolysis
Positive Regulation Of Blood Coagulation
Secretion By Cell
Acute-phase Response
Positive Regulation Of Coagulation
Response To Stress
DNA-templated Transcription, Initiation
Positive Regulation Of Wound Healing
Regulation Of Metabolic Process
Secretion
Mating
Negative Regulation Of Blood Coagulation
Cell Activation
Regulation Of Inflammatory Response
Negative Regulation Of Coagulation
Negative Regulation Of Integrin Biosynthetic Process
Regulation Of Blood Coagulation, Intrinsic Pathway
Tagcloud
?
422a
akt3
circuit
differentially
dysregulated
effectors
encode
gleason
grades
kallikrein
kallikreins
klk14
klk15
klk3
klk4
micrornas
microsatellite
minisatellite
mirna
mirnas
nucleotides
pik3cg
prostate
proteases
pseudogene
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