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KCNQ1
Gene Name
potassium channel, voltage gated KQT-like subfamily Q, member 1
Image
Gene Ontology Annotations
Cellular Component
Lysosome
Early Endosome
Late Endosome
Plasma Membrane
Voltage-gated Potassium Channel Complex
Basolateral Plasma Membrane
Cytoplasmic Vesicle Membrane
Molecular Function
Voltage-gated Potassium Channel Activity
Delayed Rectifier Potassium Channel Activity
Protein Binding
Calmodulin Binding
Protein Phosphatase 1 Binding
Protein Kinase A Catalytic Subunit Binding
Protein Kinase A Regulatory Subunit Binding
Ion Channel Binding
Voltage-gated Potassium Channel Activity Involved In Cardiac Muscle Cell Action Potential Repolarization
Voltage-gated Potassium Channel Activity Involved In Atrial Cardiac Muscle Cell Action Potential Repolarization
Scaffold Protein Binding
Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization
Biological Process
Regulation Of Gene Expression By Genetic Imprinting
Synaptic Transmission
Sensory Perception Of Sound
Regulation Of Heart Contraction
Positive Regulation Of Heart Rate
Gene Silencing
Cellular Response To Drug
Cardiac Muscle Contraction
Regulation Of Membrane Repolarization
Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization
Regulation Of Atrial Cardiac Muscle Cell Membrane Repolarization
Positive Regulation Of Cardiac Muscle Contraction
Cellular Response To CAMP
Potassium Ion Export
Potassium Ion Transmembrane Transport
Cellular Response To Epinephrine Stimulus
Cardiovascular System Development
Ventricular Cardiac Muscle Cell Action Potential
Membrane Repolarization During Action Potential
Membrane Repolarization During Cardiac Muscle Cell Action Potential
Atrial Cardiac Muscle Cell Action Potential
Regulation Of Heart Rate By Cardiac Conduction
Potassium Ion Export Across Plasma Membrane
Positive Regulation Of Potassium Ion Transmembrane Transport
Pathways
Potassium Channels
Voltage gated Potassium channels
Drugs
Indapamide
Bepridil
Diseases
GWAS
Electrocardiographic traits (
20062063
)
Height (
20881960
)
Platelet aggregation (
20526338
)
Protein quantitative trait loci (
18464913
)
QT interval (
23166209
19305408
19305409
)
Type 2 diabetes (
21573907
18711366
18711367
21799836
22961080
20581827
19401414
20174558
)
Protein-protein Interactions
7 interactors:
AKAP9
KCNE1
KCNE2
KCNE4
PPP1CA
PRKACA
TRAF6
Entrez ID
3784
HPRD ID
06341
Ensembl ID
ENSG00000053918
Uniprot IDs
P51787
Q96AI9
PDB IDs
3BJ4
3HFC
3HFE
Enriched GO Terms of Interacting Partners
?
Cardiac Conduction
Regulation Of Heart Rate
Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization
Regulation Of Membrane Repolarization
Regulation Of Heart Rate By Cardiac Conduction
Regulation Of Ion Transmembrane Transport
Regulation Of Ion Transmembrane Transporter Activity
Regulation Of Transmembrane Transporter Activity
Regulation Of Potassium Ion Transmembrane Transporter Activity
Regulation Of Heart Contraction
Regulation Of Potassium Ion Transmembrane Transport
Regulation Of Ion Transport
Regulation Of Potassium Ion Transport
Regulation Of Cardiac Muscle Contraction
Regulation Of Cation Channel Activity
Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway
Regulation Of Striated Muscle Contraction
Regulation Of Delayed Rectifier Potassium Channel Activity
Membrane Repolarization During Cardiac Muscle Cell Action Potential
Membrane Repolarization During Action Potential
Potassium Ion Export
Membrane Repolarization
Regulation Of Muscle Contraction
Positive Regulation Of Potassium Ion Transmembrane Transport
Ventricular Cardiac Muscle Cell Action Potential
Regulation Of Lipopolysaccharide-mediated Signaling Pathway
Triglyceride Catabolic Process
Potassium Ion Transmembrane Transport
Acylglycerol Catabolic Process
Potassium Ion Transport
Cardiac Muscle Cell Action Potential Involved In Contraction
Positive Regulation Of Potassium Ion Transport
Cardiac Muscle Cell Action Potential
Regulation Of Membrane Potential
Cellular Response To Organic Substance
Regulation Of Cardiac Muscle Cell Contraction
Cellular Response To CAMP
Positive Regulation Of Myeloid Leukocyte Differentiation
Epithelium Development
Epithelial Tube Morphogenesis
Positive Regulation Of Cellular Protein Metabolic Process
Cellular Response To Organic Cyclic Compound
Tube Morphogenesis
Positive Regulation Of Myeloid Cell Differentiation
Positive Regulation Of Ion Transmembrane Transport
Positive Regulation Of Protein Metabolic Process
Response To Organic Substance
Cellular Response To Organonitrogen Compound
Response To Interleukin-1
Action Potential
Tagcloud
?
amide
arrhythmias
backbone
deafness
foundation
gated
helical
helices
hypotheses
inherited
kcne
kv7
kvlqt1
lay
lyso
micelles
palmitoylphosphatidylglycerol
s0
s1
s4
shares
spans
testable
tetraspan
topology
voltage
vsd
vsds