KCNA1

Gene Name		potassium channel, voltage gated shaker related subfamily A, member 1
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Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Cytosol Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Cell Surface Integral Component Of Membrane Apical Plasma Membrane Cell Junction Dendrite Paranode Region Of Axon Presynaptic Membrane Neuronal Cell Body Axon Terminus Juxtaparanode Region Of Axon Synapse
	Molecular Function	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding Potassium Ion Transmembrane Transporter Activity
	Biological Process	Potassium Ion Transport Regulation Of Muscle Contraction Synaptic Transmission Cell Communication By Electrical Coupling Magnesium Ion Homeostasis Neuronal Action Potential Neuronal Signal Transduction Regulation Of Ion Transmembrane Transport Regulation Of Membrane Potential Neuromuscular Process Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Detection Of Mechanical Stimulus Involved In Sensory Perception Of Touch Protein Homooligomerization Cellular Response To Magnesium Ion Potassium Ion Transmembrane Transport
Pathways		Potassium Channels Voltage gated Potassium channels
Drugs		Enflurane Amitriptyline Isoflurane Methoxyflurane Nifedipine Desflurane Sevoflurane Dalfampridine
Diseases
GWAS
Protein-protein Interactions		3 interactors: DLG1 DLG4 KCNE4
Entrez ID		3736
HPRD ID		08885
Ensembl ID		ENSG00000111262
Uniprot IDs		Q09470
PDB IDs		2AFL
Enriched GO Terms of Interacting Partners?		Receptor Localization To Synapse Protein Localization To Synapse Cortical Actin Cytoskeleton Organization Establishment Or Maintenance Of Apical/basal Cell Polarity Cortical Cytoskeleton Organization Regulation Of Ion Transmembrane Transport Receptor Clustering Nucleotide Phosphorylation Regulation Of Ion Transport Establishment Or Maintenance Of Cell Polarity Regulation Of Membrane Potential T Cell Cytokine Production Hard Palate Development Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of Grooming Behavior Protein Localization To Membrane Maintenance Of Apical/basal Cell Polarity Axon Guidance Negative Regulation Of Receptor Internalization Peristalsis Cytokine Production Involved In Immune Response Immunological Synapse Formation Locomotory Exploration Behavior Dendritic Spine Morphogenesis Synaptic Vesicle Maturation Maintenance Of Cell Polarity Axonogenesis Nucleotide Metabolic Process Axon Development Vocalization Behavior Cell Morphogenesis Involved In Neuron Differentiation Synaptic Transmission Amyloid Precursor Protein Metabolic Process Chemotaxis Actin Cytoskeleton Organization Membrane Raft Organization Dendritic Spine Development Neuron Projection Morphogenesis Endothelial Cell Proliferation Actin Filament-based Process Nucleobase-containing Small Molecule Metabolic Process Negative Regulation Of Receptor-mediated Endocytosis Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Dendritic Spine Organization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Cell Morphogenesis Involved In Differentiation Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Plasma Membrane Exploration Behavior Postsynaptic Membrane Organization
Tagcloud ?		channel classes custom excitability gated genotyping gmm haplotype intriguing inwardly kcnd2 kcnj3 kcnj6 kcnk9 latent member membership mild monthly pain persistent postsurgical potassium rectifying snps subfamily variations voltage warrant