IGFBP6

Gene Name		insulin-like growth factor binding protein 6
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Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Apparatus Extracellular Vesicular Exosome
	Molecular Function	Insulin-like Growth Factor I Binding Insulin-like Growth Factor II Binding
	Biological Process	Regulation Of Cell Growth Signal Transduction Negative Regulation Of Cell Proliferation Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Cellular Protein Metabolic Process
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: IGF1 IGF2 TF UBQLN4
Entrez ID		3489
HPRD ID		00902
Ensembl ID		ENSG00000167779
Uniprot IDs		P24592
PDB IDs		1RMJ
Enriched GO Terms of Interacting Partners?		Platelet Degranulation Exocrine Pancreas Development Positive Regulation Of Glycogen Biosynthetic Process Platelet Activation Positive Regulation Of Activated T Cell Proliferation Regulation Of Glycogen Biosynthetic Process Exocytosis Positive Regulation Of Glucose Metabolic Process Regulation Of Activated T Cell Proliferation Regulation Of Glycogen Metabolic Process Positive Regulation Of Mitotic Nuclear Division Blood Coagulation Hemostasis Exocrine System Development Secretion By Cell Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Body Fluid Levels Positive Regulation Of Protein Kinase B Signaling Wound Healing Positive Regulation Of T Cell Proliferation Secretion Cell Activation Pancreas Development Response To Wounding Regulation Of Glucose Metabolic Process Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Nuclear Division Regulation Of Protein Kinase B Signaling Positive Regulation Of Cell Division Regulation Of T Cell Proliferation Digestive System Development Regulation Of Carbohydrate Metabolic Process Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of T Cell Activation Regulation Of Peptidyl-tyrosine Phosphorylation Prostate Gland Stromal Morphogenesis Glycolate Metabolic Process Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell Cycle Process Striated Muscle Cell Differentiation Negative Regulation Of Oocyte Development Insulin Receptor Signaling Pathway Via Phosphatidylinositol 3-kinase Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Positive Regulation Of Cell-cell Adhesion Regulation Of Cell Division Positive Regulation Of Glycogen (starch) Synthase Activity Ossification Positive Regulation Of Cell Cycle
Tagcloud ?		1ra afgf basement c5a cyr61 endocan endoglin endostatin engelbreth fetuin gelled holm interpretations lipocalin matrigel mig osteopontin pentraxin plgf rbp4 resistin serpin sicam swarm timp xviii