HPN

Gene Name		hepsin
Image
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Cell Surface Integral Component Of Membrane Nuclear Membrane Neuronal Cell Body Extracellular Vesicular Exosome
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Calcium-activated Potassium Channel Activity Serine-type Exopeptidase Activity
	Biological Process	Proteolysis Regulation Of Cell Shape Positive Regulation Of Gene Expression Negative Regulation Of Alkaline Phosphatase Activity Negative Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Plasminogen Activation Positive Regulation Of Cell Growth Basement Membrane Disassembly Cholesterol Homeostasis Negative Regulation Of Apoptotic Process Positive Regulation By Host Of Viral Transcription Negative Regulation Of Epithelial Cell Proliferation Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Potassium Ion Transmembrane Transport Cochlea Morphogenesis Response To Thyroid Hormone Pilomotor Reflex Positive Regulation Of Hepatocyte Proliferation Positive Regulation Of Thyroid Hormone Generation
Pathways
Drugs
Diseases
GWAS		Serum albumin level ( 23022100)
Protein-protein Interactions		3 interactors: F7 GLP1R HGF
Entrez ID		3249
HPRD ID		00801
Ensembl ID		ENSG00000105707
Uniprot IDs		B7Z1L4 P05981
PDB IDs		1O5E 1O5F 1P57 1Z8G 3T2N
Enriched GO Terms of Interacting Partners?		Organ Regeneration Response To Vitamin K Positive Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Myoblast Proliferation Blood Coagulation, Extrinsic Pathway Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Hepatocyte Growth Factor Receptor Signaling Pathway Blood Coagulation Hemostasis Cellular Response To Hepatocyte Growth Factor Stimulus Regulation Of Branching Involved In Salivary Gland Morphogenesis By Mesenchymal-epithelial Signaling Response To Peptide Hormone Positive Regulation Of Myelination Response To Peptide Response To Organic Substance Positive Regulation Of Neuron Projection Regeneration Negative Regulation Of Hydrogen Peroxide-induced Cell Death Regulation Of Hydrogen Peroxide-induced Cell Death Peptidyl-glutamic Acid Carboxylation Mesenchymal-epithelial Cell Signaling Regulation Of Body Fluid Levels Regulation Of Cell Migration Regulation Of Branching Involved In Salivary Gland Morphogenesis Wound Healing Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Cell Motility Negative Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Signaling Regulation Of Locomotion Positive Regulation Of DNA Biosynthetic Process Regulation Of Cellular Component Movement Response To Wounding CAMP-mediated Signaling Response To Stress Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Oxidative Stress-induced Cell Death Positive Chemotaxis Response To Organonitrogen Compound Activation Of Adenylate Cyclase Activity Cyclic-nucleotide-mediated Signaling Regulation Of Response To Reactive Oxygen Species Positive Regulation Of Positive Chemotaxis Positive Regulation Of Blood Coagulation Negative Regulation Of Mitochondrion Organization Positive Regulation Of Adenylate Cyclase Activity
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