HSD17B10

Gene Name		hydroxysteroid (17-beta) dehydrogenase 10
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Endoplasmic Reticulum Plasma Membrane
	Molecular Function	3-hydroxyacyl-CoA Dehydrogenase Activity Protein Binding Cholate 7-alpha-dehydrogenase Activity Testosterone Dehydrogenase [NAD(P)] Activity Poly(A) RNA Binding 3-hydroxy-2-methylbutyryl-CoA Dehydrogenase Activity
	Biological Process	Lipid Metabolic Process TRNA Processing Branched-chain Amino Acid Catabolic Process Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Oxidation-reduction Process
Pathways		Branched-chain amino acid catabolism Metabolism of amino acids and derivatives
Drugs		NADH Nicotinamide-Adenine-Dinucleotide 1-Azepan-1-Yl-2-Phenyl-2-(4-Thioxo-1,4-Dihydro-Pyrazolo[3,4-D]Pyrimidin-5-Yl)Ethanone Adduct
Diseases
GWAS
Protein-protein Interactions		5 interactors: APP CHD3 FAF1 HTRA2 UBE2D1
Entrez ID		3028
HPRD ID		02223
Ensembl ID		ENSG00000072506
Uniprot IDs		Q99714
PDB IDs		1F67 1SO8 1U7T 2O23
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteolysis Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Cellular Protein Catabolic Process Protein Catabolic Process Regulation Of Multicellular Organism Growth Pentacyclic Triterpenoid Metabolic Process Regulation Of Proteolysis Regulation Of Cellular Protein Metabolic Process Adult Locomotory Behavior Regulation Of Protein Metabolic Process Positive Regulation Of Peptidase Activity Synaptic Growth At Neuromuscular Junction Cellular Macromolecule Catabolic Process Regulation Of Catalytic Activity Adult Behavior Regulation Of Cell Cycle Collateral Sprouting In Absence Of Injury Apoptotic Process Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Programmed Cell Death Cell Death Death Regulation Of Mitotic Cell Cycle Phase Transition Response To Abiotic Stimulus Regulation Of Cell Cycle Phase Transition Locomotory Behavior Positive Regulation Of Cellular Protein Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Protein Metabolic Process Axon Choice Point Recognition Cytoplasmic Sequestering Of NF-kappaB Regulation Of Developmental Growth Neuron Remodeling Response To Herbicide Protein Autoprocessing Regulation Of Mitochondrion Degradation Negative Regulation Of Proteolysis Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Negative Regulation Of Protein Processing Proteolysis Positive Regulation Of Catalytic Activity Regulation Of Endopeptidase Activity Regulation Of Protein Catabolic Process Regulation Of Protein Processing Regulation Of Peptidase Activity
Tagcloud ?		10c 17beta abad abnormally abound allopregnanolone alternate avenue belief catalyzes dehydrogenase homotetrameric hydroxysteroid infantile isoleucine misconceptions misnomer missense mistaken multifunctional negligible neuroactive opened predicated properly psychomotor steroids xp11