KLK5

Description		kallikrein related peptidase 5
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytosol Secretory Granule Epidermal Lamellar Body
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity
	Biological Process	Positive Regulation Of Antibacterial Peptide Production Proteolysis Epidermis Development Extracellular Matrix Disassembly Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Protein Maturation Cornification Amelogenesis
Pathways		Formation of the cornified envelope Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs
Diseases
GWAS
Interacting Genes		12 interacting genes: AURKA BAG4 CASP8 DSG1 ERBB2 ESR1 IGF1R MANBAL NOTCH2 SERPINA1 TGFB1 TSG101
Entrez ID		25818
HPRD ID		05732
Ensembl ID		ENSG00000167754
Uniprot IDs		Q9Y337
PDB IDs		2PSX 2PSY 6QFE 7U5B
Enriched GO Terms of Interacting Partners?		Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Intracellular Signal Transduction Positive Regulation Of Myeloid Leukocyte Differentiation Negative Regulation Of Apoptotic Process Response To Wounding Regulation Of MiRNA Transcription Regulation Of Signal Transduction Regulation Of MiRNA Metabolic Process Positive Regulation Of Macrophage Differentiation Response To Estradiol Regulation Of Cell Communication Positive Regulation Of Intracellular Signal Transduction Ubiquitin Protein Ligase Binding Positive Regulation Of Myeloid Cell Differentiation Regulation Of Signaling Plasma Membrane Branch Elongation Of An Epithelium Liver Development Positive Regulation Of Fibroblast Migration Axis Elongation Protein-containing Complex Binding Branching Involved In Mammary Gland Duct Morphogenesis Regulation Of Myeloid Leukocyte Differentiation Developmental Growth Developmental Growth Involved In Morphogenesis Myeloid Dendritic Cell Differentiation Positive Regulation Of Smooth Muscle Cell Differentiation Myeloid Leukocyte Differentiation Regulation Of Macrophage Differentiation Positive Regulation Of Cell Development Regulation Of Cell Development Regulation Of Hemopoiesis Animal Organ Development Negative Regulation Of MiRNA Transcription Myeloid Dendritic Cell Activation Gland Morphogenesis Liver Regeneration Lymphocyte Activation Positive Regulation Of MAPK Cascade Plasma Membrane Bounded Cell Projection Organization Maternal Process Involved In Female Pregnancy Epithelial Cell Proliferation Positive Regulation Of Cell Population Proliferation Response To Progesterone Positive Regulation Of Leukocyte Differentiation Receptor Complex Positive Regulation Of Epithelial Cell Proliferation Dendritic Cell Differentiation
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