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PMPCA

Gene Name peptidase (mitochondrial processing) alpha
Image No pdb structure
Gene Ontology Annotations Cellular Component
  • Extracellular Space
  • Mitochondrion
  • Mitochondrial Inner Membrane
  • Mitochondrial Matrix
Molecular Function
  • Metalloendopeptidase Activity
  • Metal Ion Binding
Biological Process
  • Proteolysis
  • Protein Targeting To Mitochondrion
  • Cellular Protein Metabolic Process
Pathways
  • Mitochondrial protein import
Drugs
Diseases
GWAS
  • Inflammatory bowel disease ( 23128233)
Protein-protein Interactions 3 interactors: BMPR2 PMPCB SKIV2L
Entrez ID 23203
HPRD ID 07500
Ensembl ID ENSG00000165688
Uniprot IDs Q10713
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Regulation Of Lung Blood Pressure
  • Negative Regulation Of Chondrocyte Proliferation
  • Negative Regulation Of Vasoconstriction
  • Positive Regulation Of Axon Extension Involved In Axon Guidance
  • Lymphatic Endothelial Cell Differentiation
  • Lymphangiogenesis
  • Lymph Vessel Morphogenesis
  • Regulation Of Axon Extension Involved In Axon Guidance
  • Venous Blood Vessel Development
  • Retina Vasculature Development In Camera-type Eye
  • Lymph Vessel Development
  • Negative Regulation Of Systemic Arterial Blood Pressure
  • Negative Regulation Of DNA Biosynthetic Process
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