PMPCA and NDOR1

		PMPCA	NDOR1
Description		peptidase, mitochondrial processing subunit alpha	NADPH dependent diflavin oxidoreductase 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane Mitochondrial Processing Peptidase Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Intermediate Filament Cytoskeleton Perinuclear Region Of Cytoplasm
	Molecular Function	Metalloendopeptidase Activity Protein Binding Metal Ion Binding	NADPH-hemoprotein Reductase Activity Protein Binding Electron Transfer Activity FMN Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On NAD(P)H Oxidoreductase Activity, Acting On NAD(P)H, Heme Protein As Acceptor Flavin Adenine Dinucleotide Binding NADP Binding NADPH Binding FAD Binding NADPH-iron-sulfur [2Fe-2S] Protein Oxidoreductase Activity
	Biological Process	Proteolysis Protein Processing Involved In Protein Targeting To Mitochondrion Protein Processing	Iron-sulfur Cluster Assembly Electron Transport Chain
Pathways		Mitochondrial protein import Processing of SMDT1 Mitochondrial protein degradation	Cytosolic iron-sulfur cluster assembly
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Chronotype ( 30696823) Crohn's disease ( 28067908) Granulocyte count ( 27863252) Inflammatory bowel disease ( 23128233 28067908) Joint damage in rheumatoid arthritis ( 26498133) LDL cholesterol levels ( 32203549) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Serum total protein levels ( 29403010) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Ulcerative colitis ( 28067908) White blood cell count ( 27863252)	Estimated glomerular filtration rate ( 31152163) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular hemoglobin concentration ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494)
Interacting Genes		6 interacting genes: BMPR2 LINC01554 OGT PMPCB SKIC2 ZNF76	29 interacting genes: C7orf57 CCDC33 CENATAC CYCS DLG4 DRC4 EFHC2 ENOX2 GPS2 HOXB2 KIAA0408 LMO2 LMO3 LNX1 MEOX1 MTUS2 NAB2 NLK PSMB6 TCF4 TCHP TEPSIN TLE5 UBQLN1 UBQLN2 ZBTB42 ZC2HC1C ZNF620 ZNF774
Entrez ID		23203	27158
HPRD ID		07500	10444
Ensembl ID		ENSG00000165688	ENSG00000188566
Uniprot IDs		Q10713 Q5SXN9	Q9UHB4
PDB IDs			4H2D
Enriched GO Terms of Interacting Partners?		Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Synapse
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