EYA2

Gene Name		EYA transcriptional coactivator and phosphatase 2
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Centrosome
	Molecular Function	Magnesium Ion Binding Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	DNA Repair Transcription, DNA-templated Regulation Of Transcription, DNA-templated Mesodermal Cell Fate Specification Striated Muscle Tissue Development Histone Dephosphorylation Peptidyl-tyrosine Dephosphorylation Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Mitochondrial Outer Membrane Permeabilization
Pathways
Drugs
Diseases
GWAS		Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Protein-protein Interactions		6 interactors: DMRTB1 GNAI2 GNAZ RBPMS SIX1 SIX4
Entrez ID		2139
HPRD ID		09041
Ensembl ID		ENSG00000064655
Uniprot IDs		O00167
PDB IDs		3GEB 3HB0 3HB1 4EGC
Enriched GO Terms of Interacting Partners?		Myotome Development Positive Regulation Of Ureteric Bud Formation Regulation Of Branch Elongation Involved In Ureteric Bud Branching Regulation Of Synaptic Growth At Neuromuscular Junction Olfactory Placode Formation Trigeminal Ganglion Development Myoblast Migration Fungiform Papilla Morphogenesis Fungiform Papilla Development Ganglion Development Regulation Of Skeletal Muscle Cell Differentiation Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Metanephric Mesenchyme Development Tongue Morphogenesis Nose Development Regulation Of Branching Involved In Ureteric Bud Morphogenesis Pharyngeal System Development Positive Regulation Of Embryonic Development Positive Regulation Of Kidney Development Tongue Development Muscle Cell Migration Cranial Nerve Development Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Thymus Development Regulation Of Synapse Assembly Embryonic Cranial Skeleton Morphogenesis Regulation Of Morphogenesis Of A Branching Structure Regulation Of Skeletal Muscle Tissue Development Regulation Of Synapse Organization Regulation Of Synapse Structure Or Activity Nerve Development Somite Development Inner Ear Morphogenesis Metanephros Development Regulation Of Embryonic Development Ear Morphogenesis Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Embryonic Skeletal System Morphogenesis Regulation Of Striated Muscle Tissue Development Negative Regulation Of Satellite Cell Differentiation Skeletal Muscle Fiber Differentiation Skeletal Muscle Tissue Development G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Skeletal Muscle Organ Development Regulation Of Protein Localization Embryonic Skeletal System Development Protein Localization To Nucleus Negative Regulation Of Neuron Apoptotic Process Regulation Of Organ Morphogenesis Inner Ear Development
Tagcloud ?		atoh1 atoh1a atoh1and conditional coregulate crest determinant ear elusive fate fgf fgfr fgfs ganglia hair ontogeny otic postfertilization sag segmentation seq sox9 sox9a specify statoacoustic tlx2 ultricular uncovered zebrafish