ADARB1

Gene Name		adenosine deaminase, RNA-specific, B1
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	RNA Binding Double-stranded RNA Binding Double-stranded RNA Adenosine Deaminase Activity MRNA Binding Adenosine Deaminase Activity Protein Binding Poly(A) RNA Binding Metal Ion Binding
	Biological Process	Adenosine To Inosine Editing RNA Processing MRNA Processing Negative Regulation Of Cell Proliferation Gene Expression Base Conversion Or Substitution Editing MRNA Modification Negative Regulation Of Cell Migration Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Positive Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Regulation Of Cell Cycle
Pathways		Formation of editosomes by ADAR proteins mRNA Editing: A to I Conversion C6 deamination of adenosine mRNA Editing
Drugs
Diseases
GWAS		Pulmonary function ( 17903307)
Protein-protein Interactions		2 interactors: APP PIN1
Entrez ID		104
HPRD ID		06777
Ensembl ID		ENSG00000197381
Uniprot IDs		P78563 Q4AE77
PDB IDs		1ZY7
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Regulation Of Mitotic Cell Cycle Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Cell Cycle Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Innate Immune Response Cellular Copper Ion Homeostasis Regulation Of Cell Cycle Copper Ion Homeostasis Suckling Behavior Positive Regulation Of Hydrolase Activity Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Positive Regulation Of Protein Metabolic Process Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Immune Response RNA Polyadenylation Neuron Recognition Regulation Of Phosphorylation Defense Response Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Negative Regulation Of Type I Interferon Production Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Phosphorus Metabolic Process Positive Regulation Of Catalytic Activity Axon Cargo Transport Mating Neuromuscular Junction Development Regulation Of Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of ERK1 And ERK2 Cascade Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition Regulation Of Cytokinesis Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death
Tagcloud ?		21q22 a890v affective already bipolar cent chromosomal coding conformation connected decreasing disorder entire except exclude fragment linkage lithium locus polymorphism r755c restriction screened screening strand substitutions transition transitions trpm2