SC5D and VGLL1

		SC5D	VGLL1
Description		sterol-C5-desaturase	vestigial like family member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Nucleus Nucleoplasm
	Molecular Function	C-5 Sterol Desaturase Activity Iron Ion Binding Oxidoreductase Activity Delta7-sterol 5(6)-desaturase Activity	Transcription Coactivator Activity Protein Binding
	Biological Process	Lipid Metabolic Process Steroid Biosynthetic Process Cholesterol Biosynthetic Process Steroid Metabolic Process Lipid Biosynthetic Process Sterol Biosynthetic Process Cholesterol Biosynthetic Process Via Desmosterol Cholesterol Biosynthetic Process Via Lathosterol Negative Regulation Of Ferroptosis	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription
Pathways		Activation of gene expression by SREBF (SREBP) Cholesterol biosynthesis via desmosterol Cholesterol biosynthesis via lathosterol
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: CGREF1 FRMD5 RPS25 SCN4B SLC19A2 UBE4A VGLL1	17 interacting genes: AIRIM CDKN2D HNRNPF LONRF1 MEIS2 PFDN5 PTK7 RIPPLY1 SC5D TEAD1 TEAD2 TEAD3 TEAD4 TEKT4 TLE5 TRIM23 TSSK3
Entrez ID		6309	51442
HPRD ID		09078	06751
Ensembl ID		ENSG00000109929	ENSG00000102243
Uniprot IDs		O75845	Q99990
PDB IDs
Enriched GO Terms of Interacting Partners?		Voltage-gated Sodium Channel Activity Involved In Cardiac Muscle Cell Action Potential AV Node Cell Action Potential Pyridoxine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Folic Acid Transmembrane Transporter Activity Thiamine Diphosphate Metabolic Process Thiamine Diphosphate Biosynthetic Process Thiamine Transmembrane Transport Vitamin Transmembrane Transporter Activity Thiamine-containing Compound Metabolic Process Folic Acid Transport	Hippo Signaling TEAD-YAP Complex Embryonic Organ Development Transcription Regulator Complex Response To Retinoic Acid
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