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RPA2 and SLC17A9
Number of citations of the paper that reports this interaction (PubMedID
21988832
)
38
Data Source:
BioGRID
(two hybrid)
RPA2
SLC17A9
Description
replication protein A2
solute carrier family 17 member 9
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Chromatin
Nucleus
Nucleoplasm
DNA Replication Factor A Complex
Nuclear Body
PML Body
Site Of Double-strand Break
Lysosome
Lysosomal Membrane
Membrane
Secretory Granule
Transport Vesicle Membrane
Cytoplasmic Vesicle
Chromaffin Granule Membrane
Mucin Granule
Molecular Function
DNA Binding
Damaged DNA Binding
Single-stranded DNA Binding
Protein Binding
Enzyme Binding
Protein Phosphatase Binding
Ubiquitin Protein Ligase Binding
Telomeric DNA Binding
G-rich Strand Telomeric DNA Binding
Guanine Nucleotide Transmembrane Transporter Activity
ATP Transmembrane Transporter Activity
Protein Binding
ADP Transmembrane Transporter Activity
Transmembrane Transporter Activity
Purine Nucleotide Uniporter Activity
Biological Process
DNA Damage Checkpoint Signaling
Telomere Maintenance
Double-strand Break Repair Via Homologous Recombination
DNA Replication
DNA Repair
Base-excision Repair
Nucleotide-excision Repair
Mismatch Repair
DNA Recombination
DNA Damage Response
Regulation Of Double-strand Break Repair Via Homologous Recombination
Mitotic G1 DNA Damage Checkpoint Signaling
Protein Localization To Chromosome
Regulation Of DNA Damage Checkpoint
ADP Transport
ATP Transport
Transmembrane Transport
Purine-containing Compound Transmembrane Transport
Purine Nucleotide Import Into Lysosome
Guanine Nucleotide Transmembrane Transport
ATP Export
Lysosomal Protein Catabolic Process
Pathways
Translesion synthesis by REV1
Recognition of DNA damage by PCNA-containing replication complex
Translesion Synthesis by POLH
Removal of the Flap Intermediate from the C-strand
Activation of ATR in response to replication stress
Regulation of HSF1-mediated heat shock response
HSF1 activation
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
PCNA-Dependent Long Patch Base Excision Repair
Translesion synthesis by POLK
Translesion synthesis by POLI
Termination of translesion DNA synthesis
HDR through Single Strand Annealing (SSA)
HDR through Homologous Recombination (HRR)
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
Formation of Incision Complex in GG-NER
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Fanconi Anemia Pathway
Regulation of TP53 Activity through Phosphorylation
Activation of the pre-replicative complex
Removal of the Flap Intermediate
G2/M DNA damage checkpoint
Meiotic recombination
Impaired BRCA2 binding to RAD51
Drugs
Diseases
GWAS
HDL cholesterol levels (
32203549
)
Platelet count (
32888494
)
Plateletcrit (
32888494
)
White blood cell count (
32888494
)
Anti-Toxoplasma gondii IgG seropositivity (
30610941
)
Interacting Genes
69 interacting genes:
ACP5
AKAP9
APP
ATM
CALCOCO2
CASK
CCNC
CCNO
CDK1
CEBPA
CEP126
CFB
COPS6
CRMP1
DMRTB1
EEF1A1
ERCC1
ERCC4
EXOSC7
GAPDH
GOLM1
HERPUD1
HIRA
HNRNPUL1
HUS1
LNX2
LRIF1
MARK2
MCM2
MCM5
MED31
MEN1
NDEL1
ORC1
ORC2
ORC5
PCM1
PIAS1
PIAS4
PRC1
PRKDC
RAD1
RAD51
RAD52
RAD9A
RBM14
RBM48
RNF20
RNF40
RPA1
RPA3
RPLP1
SDF4
SERTAD3
SF1
SLC17A9
SMARCAL1
STAT3
TLE1
TP53
TUBB2A
UNC119
UNG
UTP14A
WAS
WRN
XPA
YWHAE
ZBTB14
7 interacting genes:
DIABLO
MTERF3
MYG1
RPA2
SCAND1
SMG9
TARS2
Entrez ID
6118
63910
HPRD ID
01566
12777
Ensembl ID
ENSG00000117748
ENSG00000101194
Uniprot IDs
B4DUL2
P15927
Q9BYT1
PDB IDs
1DPU
1L1O
1QUQ
1Z1D
2PI2
2PQA
2Z6K
3KDF
4MQV
4OU0
8RK2
9MJ5
Enriched GO Terms of Interacting Partners
?
DNA Metabolic Process
DNA Repair
Chromosome, Telomeric Region
Double-strand Break Repair
Nucleic Acid Metabolic Process
Nucleobase-containing Compound Metabolic Process
Nucleoplasm
DNA Damage Response
Double-strand Break Repair Via Homologous Recombination
Recombinational Repair
DNA Recombination
Macromolecule Metabolic Process
Response To Radiation
Nucleus
Telomere Maintenance
Response To Ionizing Radiation
Cellular Response To Stress
Cellular Response To Radiation
Nucleotide-excision Repair
Telomere Organization
DNA Replication Origin Binding
Site Of Double-strand Break
DNA Replication
Regulation Of DNA Metabolic Process
Damaged DNA Binding
Chromosome Organization
Single-stranded DNA Binding
Mitotic DNA Integrity Checkpoint Signaling
Nuclear Origin Of Replication Recognition Complex
Cellular Response To Ionizing Radiation
Regulation Of Cell Cycle
Response To Light Stimulus
Nucleotide-excision Repair Factor 1 Complex
Response To Gamma Radiation
DNA Replication Initiation
Response To Stress
Regulation Of Primary Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
UV Protection
Negative Regulation Of Cell Cycle
DNA Damage Checkpoint Signaling
DNA Replication Factor A Complex
Regulation Of Cellular Response To Stress
Response To UV
PML Body
Replicative Senescence
Mitotic DNA Damage Checkpoint Signaling
Base-excision Repair
Checkpoint Clamp Complex
Regulation Of Macromolecule Metabolic Process
Mitochondrial RNA Metabolic Process
Mitochondrial Matrix
Mitochondrial Threonyl-tRNA Aminoacylation
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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