IRF2 and NFE2L2

  • Number of citations of the paper that reports this interaction (PubMedID 32911434)
  • 1
  • Data Source:
  • BioGRID (two hybrid)

IRF2

NFE2L2

Description interferon regulatory factor 2 nuclear factor, erythroid 2 like 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute kidney injury in critical illness ( 27576016)
  • Adverse response to drug ( 30420678)
  • Chronic lymphocytic leukemia ( 28165464)
  • Hippocampal volume in Alzheimer's disease dementia ( 29274321)
  • Lewy body disease ( 25188341)
  • Night sleep phenotypes ( 27126917)
  • Nonsyndromic cleft lip ( 31609978)
  • Type 1 diabetes ( 34012112)
Interacting Genes 24 interacting genes: APP ATG7 BRD7 CSNK2A1 EP300 FKBP7 FOXK1 HMGB1 HMGN1 IRF2BP1 IRF2BP2 IRF8 KAT2A KAT2B MDM2 NFE2L2 NFKB1 PPP3CB PRKACA RELA SPI1 STAT1 TRIM55 TRIM63 80 interacting genes: APEX1 ARFIP2 ARPC2 ATF3 ATF4 ATM BPTF BRPF1 BRPF3 BTRC CASP1 CASP3 CDH1 CEBPG CERS2 CFAP299 CHD6 COPS7A CREB3 CREBBP CREBL2 CREBZF DDIT3 EIF2AK3 EIF3J ELF1 ELF3 ELF4 ELF5 ELK1 ETV1 ETV4 ETV6 FBXW11 FOSB FOSL2 GSK3B HNRNPR IRF2 JUN JUND KDM1A KEAP1 KPNA2 KPNA3 KPNA4 LEF1 MAFF MAFG MAFK MAP2K6 MAPK7 MAPK8 NCOR2 NFAT5 NFE2 NFE2L3 PAQR4 PMF1 PPARG PRKCA PRKCD RBMX REL RELA SMAD1 SP140 SPIC STAT3 SUMO1 SUMO2 TADA2A TBP TEF TNNT1 TRIM24 UBE2E2 WAC ZBTB24 ZNF396
Entrez ID 3660 4780
HPRD ID 00962 02732
Ensembl ID ENSG00000168310 ENSG00000116044
Uniprot IDs P14316 Q16236
PDB IDs 2FLU 2LZ1 3ZGC 4IFL 5WFV 6T7V
Enriched GO Terms of Interacting Partners?
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