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NFE2L2 and MAFG
Number of citations of the paper that reports this interaction (PubMedID
11013233
)
70
Data Source:
BioGRID
(fluorescent resonance energy transfer)
HPRD
(in vitro, in vivo)
NFE2L2
MAFG
Description
nuclear factor, erythroid 2 like 2
MAF bZIP transcription factor G
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Centrosome
Cytosol
Plasma Membrane
Protein-DNA Complex
Nucleus
Nucleoplasm
Molecular Function
Transcription Cis-regulatory Region Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Transcription Coregulator Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Protein Domain Specific Binding
Sequence-specific DNA Binding
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Identical Protein Binding
Protein Heterodimerization Activity
Sequence-specific Double-stranded DNA Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Inflammatory Response
Aging
Response To Lithium Ion
Proteasomal Ubiquitin-independent Protein Catabolic Process
Positive Regulation Of Gene Expression
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Positive Regulation Of Neuron Projection Development
Protein Ubiquitination
Positive Regulation Of Blood Coagulation
Endoplasmic Reticulum Unfolded Protein Response
Cellular Response To Oxidative Stress
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress
PERK-mediated Unfolded Protein Response
Cellular Response To Glucose Starvation
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Cell Redox Homeostasis
Positive Regulation Of Angiogenesis
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Embryonic Development
Aflatoxin Catabolic Process
Positive Regulation Of Glucose Import
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Cellular Response To Hydrogen Peroxide
Cellular Response To Copper Ion
Cellular Response To Tumor Necrosis Factor
Cellular Response To Xenobiotic Stimulus
Cellular Response To Fluid Shear Stress
Cellular Response To Laminar Fluid Shear Stress
Negative Regulation Of Hematopoietic Stem Cell Differentiation
Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Hydrogen Peroxide-induced Cell Death
Positive Regulation Of Glutathione Biosynthetic Process
Cellular Response To Angiotensin
Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
Regulation Of Removal Of Superoxide Radicals
Negative Regulation Of Endothelial Cell Apoptotic Process
Positive Regulation Of Reactive Oxygen Species Metabolic Process
In Utero Embryonic Development
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Gene Expression
Adult Behavior
Regulation Of Cellular PH
Regulation Of Cell Population Proliferation
Regulation Of Epidermal Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
ROS sensing by NFE2L2
ROS sensing by NFE2L2
Regulation of HMOX1 expression and activity
Heme signaling
Factors involved in megakaryocyte development and platelet production
Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Body shape index (
34021172
)
Estimated glomerular filtration rate (
31152163
31451708
30604766
)
Estimated glomerular filtration rate in non-diabetics (
31451708
)
HDL cholesterol levels (
32203549
)
Refractive error (
32231278
)
Interacting Genes
80 interacting genes:
APEX1
ARFIP2
ARPC2
ATF3
ATF4
ATM
BPTF
BRPF1
BRPF3
BTRC
CASP1
CASP3
CDH1
CEBPG
CERS2
CFAP299
CHD6
COPS7A
CREB3
CREBBP
CREBL2
CREBZF
DDIT3
EIF2AK3
EIF3J
ELF1
ELF3
ELF4
ELF5
ELK1
ETV1
ETV4
ETV6
FBXW11
FOSB
FOSL2
GSK3B
HNRNPR
IRF2
JUN
JUND
KDM1A
KEAP1
KPNA2
KPNA3
KPNA4
LEF1
MAFF
MAFG
MAFK
MAP2K6
MAPK7
MAPK8
NCOR2
NFAT5
NFE2
NFE2L3
PAQR4
PMF1
PPARG
PRKCA
PRKCD
RBMX
REL
RELA
SMAD1
SP140
SPIC
STAT3
SUMO1
SUMO2
TADA2A
TBP
TEF
TNNT1
TRIM24
UBE2E2
WAC
ZBTB24
ZNF396
26 interacting genes:
ATF3
BACH2
BATF3
CHD3
CREBBP
CYP2E1
DDIT3
GTF2A1L
HIF1A
HOMEZ
HOXD12
MAF
MAFF
MAPK3
MED31
NFE2
NFE2L1
NFE2L2
NFIL3
PAX6
PIDD1
PPP1CA
PRRX1
RBM48
SNRPN
VIM
Entrez ID
4780
4097
HPRD ID
02732
03605
Ensembl ID
ENSG00000116044
ENSG00000197063
Uniprot IDs
Q16236
A0A024R8X1
O15525
PDB IDs
2FLU
2LZ1
3ZGC
4IFL
5WFV
6T7V
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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