NFE2L2 and MAP2K6

  • Number of citations of the paper that reports this interaction (PubMedID 32911434)
  • 1
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology, fluorescent resonance energy transfer)

NFE2L2

MAP2K6

Description nuclear factor, erythroid 2 like 2 mitogen-activated protein kinase kinase 6
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Body shape index ( 34021172)
  • Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872)
  • Eye color ( 33692100)
  • Optic disc size ( 31809533)
  • Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy) ( 24554482)
  • Response to TNF-alpha inhibitors in rheumatoid arthritis ( 22569225)
  • Waist-hip ratio ( 28552196)
Interacting Genes 80 interacting genes: APEX1 ARFIP2 ARPC2 ATF3 ATF4 ATM BPTF BRPF1 BRPF3 BTRC CASP1 CASP3 CDH1 CEBPG CERS2 CFAP299 CHD6 COPS7A CREB3 CREBBP CREBL2 CREBZF DDIT3 EIF2AK3 EIF3J ELF1 ELF3 ELF4 ELF5 ELK1 ETV1 ETV4 ETV6 FBXW11 FOSB FOSL2 GSK3B HNRNPR IRF2 JUN JUND KDM1A KEAP1 KPNA2 KPNA3 KPNA4 LEF1 MAFF MAFG MAFK MAP2K6 MAPK7 MAPK8 NCOR2 NFAT5 NFE2 NFE2L3 PAQR4 PMF1 PPARG PRKCA PRKCD RBMX REL RELA SMAD1 SP140 SPIC STAT3 SUMO1 SUMO2 TADA2A TBP TEF TNNT1 TRIM24 UBE2E2 WAC ZBTB24 ZNF396 39 interacting genes: AKT1 BECN1 BRAF CCND2 CDKN2B DCTN1 EPHA2 FBXO7 FGFR4 GLIS2 HGF HRAS LRRK2 MAP2K3 MAP2K4 MAP2K5 MAP3K20 MAP3K4 MAP3K5 MAP3K7 MAPK1 MAPK12 MAPK13 MAPK14 MAPKAPK2 MLH1 NFE2L2 PICK1 PKN1 PLCB2 RAF1 RASSF1 RELA SMAD7 STAT4 STK11 TAOK2 TLR3 TRAF6
Entrez ID 4780 5608
HPRD ID 02732 03155
Ensembl ID ENSG00000116044 ENSG00000108984
Uniprot IDs Q16236 A0A024R8K3 A8K3Y2 P52564
PDB IDs 2FLU 2LZ1 3ZGC 4IFL 5WFV 6T7V 2Y8O 3ENM 3FME 3VN9 5ETF
Enriched GO Terms of Interacting Partners?
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