WDR83 and WBP4

Data Source:
BioGRID (two hybrid)

		WDR83	WBP4
Description		WD repeat domain 83	WW domain binding protein 4
Image		No pdb structure
GO Annotations	Cellular Component	Spliceosomal Complex Endosome Membrane Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome
	Molecular Function	Protein Binding	RNA Binding Protein Binding Zinc Ion Binding Proline-rich Region Binding
	Biological Process	MAPK Cascade RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Response To Hypoxia Response To Lipopolysaccharide Regulation Of I-kappaB Kinase/NF-kappaB Signaling Inflammatory Response To Wounding	MRNA Splicing, Via Spliceosome RNA Splicing MRNA Cis Splicing, Via Spliceosome
Pathways		MAP2K and MAPK activation	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Crohn's disease ( 23266558) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Intraocular pressure ( 29617998) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269)
Interacting Genes		30 interacting genes: BAG2 BCL6 CRB3 CRK EGLN3 FAM124B FRS3 GNE GPKOW HNRNPH2 HOXA1 HSPB1 KCTD9 KDM1A KEAP1 LONRF1 LSM3 NOXA1 PARD6A PARD6B PCBP2 PRKAB2 RACK1 SAP30BP SF1 TLX3 TOE1 VAC14 WBP4 ZNF76	54 interacting genes: ARGLU1 BUB3 CAPRIN1 CHERP CHTF8 CPSF6 CPSF7 DDX23 DDX3X DHX15 DHX38 DIAPH1 DNM2 EFTUD2 EWSR1 FAM50B FUS HLTF HNRNPK HNRNPU HTATSF1 ISY1 KHDRBS1 NONO PABPC1 PPIA PRPF3 PRPF4 PRPF40A PSPC1 SART1 SCAF4 SF1 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SNRNP200 SNRNP70 SNRPA SNRPB SNW1 TCERG1 TIA1 WAS WBP11 WDR83 WIPF1 XRCC6 ZC2HC1A ZNF207
Entrez ID		84292	11193
HPRD ID		14730	16086
Ensembl ID		ENSG00000123154	ENSG00000120688
Uniprot IDs		Q9BRX9	O75554
PDB IDs			2DK1 2JXW 5O9Z 6AHD
Enriched GO Terms of Interacting Partners?
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