WBP4 and CPSF7

Data Source:
BioGRID (pull down)

		WBP4	CPSF7
Description		WW domain binding protein 4	cleavage and polyadenylation specific factor 7
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome	Nucleus Nucleoplasm Cytoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex MRNA Cleavage Factor Complex Membrane
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding Proline-rich Region Binding	RNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Splicing MRNA Cis Splicing, Via Spliceosome	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA 3'-end Processing Protein Tetramerization Protein Heterotetramerization Pre-mRNA Cleavage Required For Polyadenylation MRNA Alternative Polyadenylation Messenger Ribonucleoprotein Complex Assembly
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Crohn's disease ( 23266558) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Intraocular pressure ( 29617998) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269)
Interacting Genes		54 interacting genes: ARGLU1 BUB3 CAPRIN1 CHERP CHTF8 CPSF6 CPSF7 DDX23 DDX3X DHX15 DHX38 DIAPH1 DNM2 EFTUD2 EWSR1 FAM50B FUS HLTF HNRNPK HNRNPU HTATSF1 ISY1 KHDRBS1 NONO PABPC1 PPIA PRPF3 PRPF4 PRPF40A PSPC1 SART1 SCAF4 SF1 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SNRNP200 SNRNP70 SNRPA SNRPB SNW1 TCERG1 TIA1 WAS WBP11 WDR83 WIPF1 XRCC6 ZC2HC1A ZNF207	59 interacting genes: APBB1 ARMC7 ATXN1 CATSPER1 CFAP206 CLK2 CSNK2A1 DVL2 EPM2AIP1 EWSR1 GAS8 GCC1 GRB2 GUCD1 HINT1 HNRNPF ITCH LENG8 LNX1 MIR1-1 MIR1-2 MIR10B MIR128-2 MIR141 MIR155 MIR16-1 MIR17 MIR18B MIR199A1 MIR19A MIR19B1 MIR25 MIR29C MIR34B MIR7-1 MIR9-2 MIR93 MIRLET7B NCK2 NUDT21 PATZ1 PID1 PRKAA2 PRMT2 RBM10 RUNX1T1 SEC23B SMAD3 SNRNP25 SNX18 SORBS3 SPG21 SRPK2 SUMO2 TLE5 TNS2 U2AF2 WBP4 WWOX
Entrez ID		11193	79869
HPRD ID		16086	16906
Ensembl ID		ENSG00000120688	ENSG00000149532
Uniprot IDs		O75554	B4DGF8 Q8N684
PDB IDs		2DK1 2JXW 5O9Z 6AHD	3N9U
Enriched GO Terms of Interacting Partners?
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