WBP4 and DHX15

Data Source:
BioGRID (two hybrid)

		WBP4	DHX15
Description		WW domain binding protein 4	DEAH-box helicase 15
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome	Intracellular Anatomical Structure Nucleus Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex Nucleolus Nuclear Speck U2-type Post-mRNA Release Spliceosomal Complex
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding Proline-rich Region Binding	RNA Binding RNA Helicase Activity Double-stranded RNA Binding Protein Binding ATP Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Splicing MRNA Cis Splicing, Via Spliceosome	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Response To Toxic Substance Response To Alkaloid
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Crohn's disease ( 23266558) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Intraocular pressure ( 29617998) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Myopia (pathological) ( 23049088) Pulmonary emphysema ( 24383474) Sense of smell ( 26632684)
Interacting Genes		54 interacting genes: ARGLU1 BUB3 CAPRIN1 CHERP CHTF8 CPSF6 CPSF7 DDX23 DDX3X DHX15 DHX38 DIAPH1 DNM2 EFTUD2 EWSR1 FAM50B FUS HLTF HNRNPK HNRNPU HTATSF1 ISY1 KHDRBS1 NONO PABPC1 PPIA PRPF3 PRPF4 PRPF40A PSPC1 SART1 SCAF4 SF1 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SNRNP200 SNRNP70 SNRPA SNRPB SNW1 TCERG1 TIA1 WAS WBP11 WDR83 WIPF1 XRCC6 ZC2HC1A ZNF207	21 interacting genes: AGGF1 APBB1 CAMSAP3 DDX42 DYSF FXR1 GPANK1 KRT75 NKAP NKRF PIN1 PRPF40A PTEN RBM17 SPOP TRA2A UBC WBP4 YWHAB YWHAG ZGPAT
Entrez ID		11193	1665
HPRD ID		16086	04553
Ensembl ID		ENSG00000120688	ENSG00000109606
Uniprot IDs		O75554	O43143
PDB IDs		2DK1 2JXW 5O9Z 6AHD	5XDR 6ID1 6SH6 6SH7
Enriched GO Terms of Interacting Partners?
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