WDR83 and PCBP2

Data Source:
BioGRID (two hybrid, two hybrid)

		WDR83	PCBP2
Description		WD repeat domain 83	poly(rC) binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Spliceosomal Complex Endosome Membrane Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Cytoplasm Cytosol Focal Adhesion Postsynaptic Density Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding Enzyme Binding Ubiquitin Protein Ligase Binding C-rich Single-stranded DNA Binding
	Biological Process	MAPK Cascade RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Response To Hypoxia Response To Lipopolysaccharide Regulation Of I-kappaB Kinase/NF-kappaB Signaling Inflammatory Response To Wounding	MRNA Splicing, Via Spliceosome Regulation Of Gene Expression RNA Metabolic Process MRNA Metabolic Process Negative Regulation Of Type I Interferon Production Viral RNA Genome Replication Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Innate Immune Response Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Defense Response To Virus Regulation Of RNA Metabolic Process Defense Response To Virus IRES-dependent Viral Translational Initiation
Pathways		MAP2K and MAPK activation	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS			Granulocyte percentage of myeloid white cells ( 27863252) Monocyte percentage of white cells ( 27863252) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		30 interacting genes: BAG2 BCL6 CRB3 CRK EGLN3 FAM124B FRS3 GNE GPKOW HNRNPH2 HOXA1 HSPB1 KCTD9 KDM1A KEAP1 LONRF1 LSM3 NOXA1 PARD6A PARD6B PCBP2 PRKAB2 RACK1 SAP30BP SF1 TLX3 TOE1 VAC14 WBP4 ZNF76	28 interacting genes: BARD1 CASK CNBP FLNA FTH1 HMGA1 HMGA2 HNRNPD HNRNPK HNRNPL LINC01554 NKAP PABPC1 PAXIP1 PCBP1 PRPF40A PTBP1 QKI SF3B2 SLU7 SNRPA SRSF3 SRSF7 UBC WDR77 WDR83 YBX1 YBX3
Entrez ID		84292	5094
HPRD ID		14730	03129
Ensembl ID		ENSG00000123154	ENSG00000197111
Uniprot IDs		Q9BRX9	A0A384N6B9 Q15366
PDB IDs			2AXY 2JZX 2P2R 2PQU 2PY9
Enriched GO Terms of Interacting Partners?
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