WBP4 and WDR83

Data Source:
BioGRID (two hybrid)

		WBP4	WDR83
Description		WW domain binding protein 4	WD repeat domain 83
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome	Spliceosomal Complex Endosome Membrane Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding Proline-rich Region Binding	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Splicing MRNA Cis Splicing, Via Spliceosome	MAPK Cascade RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Response To Hypoxia Response To Lipopolysaccharide Regulation Of I-kappaB Kinase/NF-kappaB Signaling Inflammatory Response To Wounding
Pathways		mRNA Splicing - Major Pathway	MAP2K and MAPK activation
Drugs
Diseases
GWAS		Crohn's disease ( 23266558) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Intraocular pressure ( 29617998) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269)
Interacting Genes		54 interacting genes: ARGLU1 BUB3 CAPRIN1 CHERP CHTF8 CPSF6 CPSF7 DDX23 DDX3X DHX15 DHX38 DIAPH1 DNM2 EFTUD2 EWSR1 FAM50B FUS HLTF HNRNPK HNRNPU HTATSF1 ISY1 KHDRBS1 NONO PABPC1 PPIA PRPF3 PRPF4 PRPF40A PSPC1 SART1 SCAF4 SF1 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SNRNP200 SNRNP70 SNRPA SNRPB SNW1 TCERG1 TIA1 WAS WBP11 WDR83 WIPF1 XRCC6 ZC2HC1A ZNF207	30 interacting genes: BAG2 BCL6 CRB3 CRK EGLN3 FAM124B FRS3 GNE GPKOW HNRNPH2 HOXA1 HSPB1 KCTD9 KDM1A KEAP1 LONRF1 LSM3 NOXA1 PARD6A PARD6B PCBP2 PRKAB2 RACK1 SAP30BP SF1 TLX3 TOE1 VAC14 WBP4 ZNF76
Entrez ID		11193	84292
HPRD ID		16086	14730
Ensembl ID		ENSG00000120688	ENSG00000123154
Uniprot IDs		O75554	Q9BRX9
PDB IDs		2DK1 2JXW 5O9Z 6AHD
Enriched GO Terms of Interacting Partners?
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