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NDEL1 and TACC3
Data Source:
BioGRID
(two hybrid, pull down, pull down)
NDEL1
TACC3
Description
nudE neurodevelopment protein 1 like 1
transforming acidic coiled-coil containing protein 3
Image
GO Annotations
Cellular Component
Kinetochore
Condensed Chromosome Kinetochore
Nuclear Envelope
Centrosome
Spindle
Cytosol
Kinesin Complex
Microtubule
Synaptic Vesicle
Cell Leading Edge
Axon Hillock
Neurofilament Cytoskeleton
Central Region Of Growth Cone
Axon Cytoplasm
Spindle Pole
Cytoplasm
Cytosol
Centriolar Satellite
Intracellular Membrane-bounded Organelle
Mitotic Spindle
Molecular Function
Protein Binding
Microtubule Binding
Identical Protein Binding
Alpha-tubulin Binding
Protein-containing Complex Binding
Beta-tubulin Binding
Oligopeptidase Activity
Protein Binding
Biological Process
Establishment Of Mitotic Spindle Orientation
Neuron Migration
Inner Cell Mass Cell Proliferation
Proteolysis
Microtubule Nucleation
Chromosome Segregation
Mitotic Centrosome Separation
Retrograde Axonal Transport
Insulin Receptor Signaling Pathway
Regulation Of Neuron Projection Development
Cell Migration
Cerebral Cortex Radially Oriented Cell Migration
Central Nervous System Neuron Axonogenesis
Lysosome Localization
Regulation Of Intracellular Protein Transport
Positive Regulation Of GTPase Activity
Positive Regulation Of Axon Extension
Vesicle Transport Along Microtubule
Positive Regulation Of Axon Regeneration
Nuclear Envelope Disassembly
Establishment Of Chromosome Localization
Centrosome Localization
Neurofilament Cytoskeleton Organization
Activation Of GTPase Activity
Positive Regulation Of Ruffle Assembly
Neuron Projection Extension
Regulation Of Microtubule Motor Activity
Microtubule Cytoskeleton Organization
Mitotic Spindle Organization
Metaphase/anaphase Transition Of Mitotic Cell Cycle
Cell Population Proliferation
Cerebral Cortex Development
Cell Division
Regulation Of Mitotic Spindle Organization
Microtubule Cytoskeleton Organization Involved In Mitosis
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
NOTCH3 Activation and Transmission of Signal to the Nucleus
Negative regulation of NOTCH4 signaling
Drugs
Diseases
GWAS
Bladder cancer (
24163127
20972438
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Mean spheric corpuscular volume (
32888494
)
Subcortical volume (MOSTest) (
32665545
)
Urinary bladder cancer (
20348956
)
Interacting Genes
88 interacting genes:
ABI3
ACTB
AIMP2
AKAP9
ANK2
APP
BMI1
BORCS6
BRK1
CASK
CCDC88A
CCSER1
CDK5
CENPF
CEP170
CEP55
CEP63
CWF19L2
DISC1
DIXDC1
DTNB
DYNC1H1
DYNC1I1
DYNLL1
FXR2
GOLGA2
IMMT
KALRN
KIF19
KIF2C
KIF5A
KIFC3
KLC4
KRT40
LUC7L2
MAGEA11
MBIP
MED11
MIS18A
MLLT10
MRC2
MTUS2
MYO5A
NDC80
PAFAH1B1
PARD6G
PARVG
PICK1
PKP2
PRC1
RBM10
RBM14
RBM5
RPA2
SLAIN1
SNAPC5
SNX6
SYNE1
TACC3
TRAF3IP3
TRIM27
TUBB
USP2
XPA
YWHAE
YWHAG
ZC2HC1C
ZNF10
ZNF12
ZNF17
ZNF180
ZNF197
ZNF211
ZNF230
ZNF250
ZNF260
ZNF264
ZNF3
ZNF35
ZNF417
ZNF490
ZNF544
ZNF572
ZNF599
ZNF662
ZNF707
ZNF844
ZNF91
29 interacting genes:
AKAP9
ARHGDIG
ARNT
ARNT2
ASPSCR1
AURKA
BEX2
BEX3
C2CD6
CCHCR1
CDC20B
CIB3
CLIP4
EIF3C
GDF15
IQCD
KAT2A
KIZ
KLC1
KLHL38
NDEL1
NOD2
NUP54
RNF20
SNX20
SPATA18
TBC1D22B
TTF2
VPS37C
Entrez ID
81565
10460
HPRD ID
06340
05601
Ensembl ID
ENSG00000166579
ENSG00000013810
Uniprot IDs
A6NIZ0
Q9GZM8
Q9Y6A5
PDB IDs
2V66
5LXN
5LXO
5ODS
5ODT
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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