NDEL1 and SLAIN1

Data Source:
BioGRID (two hybrid)

		NDEL1	SLAIN1
Description		nudE neurodevelopment protein 1 like 1	SLAIN motif family member 1
Image			No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Nuclear Envelope Centrosome Spindle Cytosol Kinesin Complex Microtubule Synaptic Vesicle Cell Leading Edge Axon Hillock Neurofilament Cytoskeleton Central Region Of Growth Cone Axon Cytoplasm	Cytoplasm Cytoskeleton
	Molecular Function	Protein Binding Microtubule Binding Identical Protein Binding Alpha-tubulin Binding Protein-containing Complex Binding Beta-tubulin Binding Oligopeptidase Activity	Protein Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Neuron Migration Inner Cell Mass Cell Proliferation Proteolysis Microtubule Nucleation Chromosome Segregation Mitotic Centrosome Separation Retrograde Axonal Transport Insulin Receptor Signaling Pathway Regulation Of Neuron Projection Development Cell Migration Cerebral Cortex Radially Oriented Cell Migration Central Nervous System Neuron Axonogenesis Lysosome Localization Regulation Of Intracellular Protein Transport Positive Regulation Of GTPase Activity Positive Regulation Of Axon Extension Vesicle Transport Along Microtubule Positive Regulation Of Axon Regeneration Nuclear Envelope Disassembly Establishment Of Chromosome Localization Centrosome Localization Neurofilament Cytoskeleton Organization Activation Of GTPase Activity Positive Regulation Of Ruffle Assembly Neuron Projection Extension Regulation Of Microtubule Motor Activity
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Blond vs. brown/black hair color ( 30531825) Brown vs. black hair color ( 30531825) Craniofacial microsomia ( 26853712) Metabolite levels ( 23823483)
Interacting Genes		88 interacting genes: ABI3 ACTB AIMP2 AKAP9 ANK2 APP BMI1 BORCS6 BRK1 CASK CCDC88A CCSER1 CDK5 CENPF CEP170 CEP55 CEP63 CWF19L2 DISC1 DIXDC1 DTNB DYNC1H1 DYNC1I1 DYNLL1 FXR2 GOLGA2 IMMT KALRN KIF19 KIF2C KIF5A KIFC3 KLC4 KRT40 LUC7L2 MAGEA11 MBIP MED11 MIS18A MLLT10 MRC2 MTUS2 MYO5A NDC80 PAFAH1B1 PARD6G PARVG PICK1 PKP2 PRC1 RBM10 RBM14 RBM5 RPA2 SLAIN1 SNAPC5 SNX6 SYNE1 TACC3 TRAF3IP3 TRIM27 TUBB USP2 XPA YWHAE YWHAG ZC2HC1C ZNF10 ZNF12 ZNF17 ZNF180 ZNF197 ZNF211 ZNF230 ZNF250 ZNF260 ZNF264 ZNF3 ZNF35 ZNF417 ZNF490 ZNF544 ZNF572 ZNF599 ZNF662 ZNF707 ZNF844 ZNF91	44 interacting genes: AKAP9 ARHGEF5 ARMC7 C1orf109 CARD9 COX5B CRACR2A DDX6 DMRTB1 EFHC1 EXOSC8 FAM214B FBXO7 FHL2 FHL3 FRS3 GOLGA1 HNRNPF HOMER3 HOXC8 HSF2BP KCTD9 KIF9 LMO3 MAPRE1 MAPRE3 NDEL1 NTAQ1 NXF1 PATZ1 PAX9 PDLIM7 PFDN5 PPP1R32 PRC1 PRPF31 PSMA3 RBM10 RBM14 RFPL3 TBC1D22B TFAP2D TSSK3 ZNF76
Entrez ID		81565	122060
HPRD ID		06340	13400
Ensembl ID		ENSG00000166579	ENSG00000139737
Uniprot IDs		A6NIZ0 Q9GZM8	A0A0A0MSS3 B7Z326 Q7L0J2 Q8ND83
PDB IDs		2V66
Enriched GO Terms of Interacting Partners?
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