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NDEL1 and CEP63
Data Source:
BioGRID
(two hybrid)
NDEL1
CEP63
Description
nudE neurodevelopment protein 1 like 1
centrosomal protein 63
Image
GO Annotations
Cellular Component
Kinetochore
Condensed Chromosome Kinetochore
Nuclear Envelope
Centrosome
Spindle
Cytosol
Kinesin Complex
Microtubule
Synaptic Vesicle
Cell Leading Edge
Axon Hillock
Neurofilament Cytoskeleton
Central Region Of Growth Cone
Axon Cytoplasm
Spindle Pole
Centrosome
Centriole
Cytosol
Molecular Function
Protein Binding
Microtubule Binding
Identical Protein Binding
Alpha-tubulin Binding
Protein-containing Complex Binding
Beta-tubulin Binding
Oligopeptidase Activity
Protein Binding
Biological Process
Establishment Of Mitotic Spindle Orientation
Neuron Migration
Inner Cell Mass Cell Proliferation
Proteolysis
Microtubule Nucleation
Chromosome Segregation
Mitotic Centrosome Separation
Retrograde Axonal Transport
Insulin Receptor Signaling Pathway
Regulation Of Neuron Projection Development
Cell Migration
Cerebral Cortex Radially Oriented Cell Migration
Central Nervous System Neuron Axonogenesis
Lysosome Localization
Regulation Of Intracellular Protein Transport
Positive Regulation Of GTPase Activity
Positive Regulation Of Axon Extension
Vesicle Transport Along Microtubule
Positive Regulation Of Axon Regeneration
Nuclear Envelope Disassembly
Establishment Of Chromosome Localization
Centrosome Localization
Neurofilament Cytoskeleton Organization
Activation Of GTPase Activity
Positive Regulation Of Ruffle Assembly
Neuron Projection Extension
Regulation Of Microtubule Motor Activity
DNA Damage Checkpoint
G2/M Transition Of Mitotic Cell Cycle
Centriole Replication
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Signal Transduction In Response To DNA Damage
Spindle Assembly
Cell Division
Ciliary Basal Body-plasma Membrane Docking
De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Diseases
GWAS
Height (
18391952
)
Late-onset Alzheimer's disease (
27770636
)
Neurocognitive impairment in HIV-1 infection (dichotomous) (
28447399
)
Waist circumference adjusted for BMI (adjusted for smoking behaviour) (
28443625
)
Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) (
28448500
)
Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) (
28443625
)
Waist circumference adjusted for BMI in active individuals (
28448500
)
Waist circumference adjusted for BMI in non-smokers (
28443625
)
Waist circumference adjusted for body mass index (
25673412
28448500
)
Interacting Genes
88 interacting genes:
ABI3
ACTB
AIMP2
AKAP9
ANK2
APP
BMI1
BORCS6
BRK1
CASK
CCDC88A
CCSER1
CDK5
CENPF
CEP170
CEP55
CEP63
CWF19L2
DISC1
DIXDC1
DTNB
DYNC1H1
DYNC1I1
DYNLL1
FXR2
GOLGA2
IMMT
KALRN
KIF19
KIF2C
KIF5A
KIFC3
KLC4
KRT40
LUC7L2
MAGEA11
MBIP
MED11
MIS18A
MLLT10
MRC2
MTUS2
MYO5A
NDC80
PAFAH1B1
PARD6G
PARVG
PICK1
PKP2
PRC1
RBM10
RBM14
RBM5
RPA2
SLAIN1
SNAPC5
SNX6
SYNE1
TACC3
TRAF3IP3
TRIM27
TUBB
USP2
XPA
YWHAE
YWHAG
ZC2HC1C
ZNF10
ZNF12
ZNF17
ZNF180
ZNF197
ZNF211
ZNF230
ZNF250
ZNF260
ZNF264
ZNF3
ZNF35
ZNF417
ZNF490
ZNF544
ZNF572
ZNF599
ZNF662
ZNF707
ZNF844
ZNF91
66 interacting genes:
ALOX5
ARFIP2
ARNT2
BFSP2
BRPF1
CAMKK2
CAPN7
CCDC14
CCDC187
CCHCR1
CCNI
CDK1
CEP57
CEP57L1
CWF19L2
DAXX
DISC1
DST
DTNB
DZIP3
EXOC4
EZH2
FAM161A
FBF1
FEM1C
GSE1
HAUS1
HGS
INTS6L
KANK2
KXD1
MACF1
MBIP
MNS1
NCOR2
NDC80
NDEL1
NXT2
PCNX4
PIBF1
POLR3C
PPP1R13B
PPP4R1
RCOR3
ROGDI
SMARCE1
SMC3
SNRNP70
SPTAN1
SPTBN1
SSX3
SYNE1
SYT17
TBC1D15
TBC1D22B
TSG101
TSGA10IP
TSHZ3
TXLNA
TXLNB
USHBP1
USP2
ZCCHC10
ZNF148
ZNF250
ZNF774
Entrez ID
81565
80254
HPRD ID
06340
07826
Ensembl ID
ENSG00000166579
ENSG00000182923
Uniprot IDs
A6NIZ0
Q9GZM8
Q96MT8
PDB IDs
2V66
6CSU
6CSV
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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