NDEL1 and ZNF572

Data Source:
BioGRID (two hybrid)

		NDEL1	ZNF572
Description		nudE neurodevelopment protein 1 like 1	zinc finger protein 572
Image			No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Nuclear Envelope Centrosome Spindle Cytosol Kinesin Complex Microtubule Synaptic Vesicle Cell Leading Edge Axon Hillock Neurofilament Cytoskeleton Central Region Of Growth Cone Axon Cytoplasm	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Microtubule Binding Identical Protein Binding Alpha-tubulin Binding Protein-containing Complex Binding Beta-tubulin Binding Oligopeptidase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Neuron Migration Inner Cell Mass Cell Proliferation Proteolysis Microtubule Nucleation Chromosome Segregation Mitotic Centrosome Separation Retrograde Axonal Transport Insulin Receptor Signaling Pathway Regulation Of Neuron Projection Development Cell Migration Cerebral Cortex Radially Oriented Cell Migration Central Nervous System Neuron Axonogenesis Lysosome Localization Regulation Of Intracellular Protein Transport Positive Regulation Of GTPase Activity Positive Regulation Of Axon Extension Vesicle Transport Along Microtubule Positive Regulation Of Axon Regeneration Nuclear Envelope Disassembly Establishment Of Chromosome Localization Centrosome Localization Neurofilament Cytoskeleton Organization Activation Of GTPase Activity Positive Regulation Of Ruffle Assembly Neuron Projection Extension Regulation Of Microtubule Motor Activity	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Metabolite levels ( 23823483)
Interacting Genes		88 interacting genes: ABI3 ACTB AIMP2 AKAP9 ANK2 APP BMI1 BORCS6 BRK1 CASK CCDC88A CCSER1 CDK5 CENPF CEP170 CEP55 CEP63 CWF19L2 DISC1 DIXDC1 DTNB DYNC1H1 DYNC1I1 DYNLL1 FXR2 GOLGA2 IMMT KALRN KIF19 KIF2C KIF5A KIFC3 KLC4 KRT40 LUC7L2 MAGEA11 MBIP MED11 MIS18A MLLT10 MRC2 MTUS2 MYO5A NDC80 PAFAH1B1 PARD6G PARVG PICK1 PKP2 PRC1 RBM10 RBM14 RBM5 RPA2 SLAIN1 SNAPC5 SNX6 SYNE1 TACC3 TRAF3IP3 TRIM27 TUBB USP2 XPA YWHAE YWHAG ZC2HC1C ZNF10 ZNF12 ZNF17 ZNF180 ZNF197 ZNF211 ZNF230 ZNF250 ZNF260 ZNF264 ZNF3 ZNF35 ZNF417 ZNF490 ZNF544 ZNF572 ZNF599 ZNF662 ZNF707 ZNF844 ZNF91	60 interacting genes: BEGAIN BOLA1 CADPS CARD9 CBY2 CCDC102B CCDC130 CCDC136 CCDC33 CDR2L CEP57L1 CEP70 CPNE7 DEUP1 FAM214B FSD2 GAS8 GOLGA2 GPR50 HAP1 HOOK1 HOOK2 IL16 KATNBL1 KIF9 KIFC3 KLC3 KRT31 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 LZTS1 LZTS2 MDFI MEOX2 MLLT3 MTUS2 NDEL1 PRPH REL SPAG5 TFIP11 TRAF1 TRAF2 TRIM27 TRIM54 VIM WTAP ZBTB1 ZBTB8A ZNF165 ZNF250 ZNF383 ZNF417 ZNF57 ZNF774 ZNF835
Entrez ID		81565	137209
HPRD ID		06340	15851
Ensembl ID		ENSG00000166579	ENSG00000180938
Uniprot IDs		A6NIZ0 Q9GZM8	Q7Z3I7
PDB IDs		2V66
Enriched GO Terms of Interacting Partners?
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