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OTUB2 and RNF126
Data Source:
BioGRID
(two hybrid)
OTUB2
RNF126
Description
OTU deubiquitinase, ubiquitin aldehyde binding 2
ring finger protein 126
Image
GO Annotations
Cellular Component
Nucleus
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Molecular Function
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
NEDD8-specific Protease Activity
Ubiquitin Binding
Epidermal Growth Factor Receptor Binding
Protein Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Biological Process
Protein Deubiquitination
Protein Phosphopantetheinylation
Protein K11-linked Deubiquitination
Protein K63-linked Deubiquitination
Protein K48-linked Deubiquitination
Negative Regulation Of Histone H2A K63-linked Ubiquitination
Negative Regulation Of Double-strand Break Repair
Ubiquitin-dependent Protein Catabolic Process
Protein Monoubiquitination
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Cell Population Proliferation
Retrograde Transport, Endosome To Golgi
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Cytoplasm Protein Quality Control By The Ubiquitin-proteasome System
Pathways
Ovarian tumor domain proteases
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Arterial stiffness (
31070453
)
Arterial stiffness index (
31235810
)
Pulse pressure (
30578418
)
Interacting Genes
42 interacting genes:
APP
ARRDC3
CDIP1
CPSF6
DAZAP2
FAM168A
GLI2
KRT31
KRT40
LZTS2
MAGEA11
MID1
MID2
MKRN1
PHLDA2
PJA1
PLEKHB2
PMEPA1
RBCK1
REL
RFFL
RNF126
SIAH1
SPART
TP53BP2
TRAF6
TRIM2
TRIM25
TRIM26
TRIM27
TRIM39
TRIM5
TRIM54
TRIM55
TRIM63
TRIM8
TRIP6
U2AF2
UBC
UBE2N
USP21
USP28
39 interacting genes:
AICDA
BAG6
CDKN1A
CENPP
CSNK2B
E2F1
EGFR
FXN
HMGCL
MAP3K1
MDM2
MIEN1
NUDT3
OTUB1
OTUB2
PLK1
PSMF1
RBX1
RNF168
SNUPN
TRIM11
TRIM23
TRIM26
TRIM52
TSG101
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E2
UBE2E3
UBE2N
UBL3
UBL4A
USP15
USP2
XRCC5
XRCC6
Entrez ID
78990
55658
HPRD ID
07620
11501
Ensembl ID
ENSG00000089723
ENSG00000070423
Uniprot IDs
Q96DC9
A0A024R206
A8K0Q1
Q9BV68
PDB IDs
1TFF
4FJV
5QIO
5QIP
5QIQ
5QIR
5QIS
5QIT
5QIU
5QIV
5QIW
5QIX
5QIY
5QIZ
2N9O
2N9P
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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