OTUB2 and PHLDA2

Data Source:
BioGRID (two hybrid)

		OTUB2	PHLDA2
Description		OTU deubiquitinase, ubiquitin aldehyde binding 2	pleckstrin homology like domain family A member 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Membrane
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding NEDD8-specific Protease Activity Ubiquitin Binding	Protein Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Protein Deubiquitination Protein Phosphopantetheinylation Protein K11-linked Deubiquitination Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Negative Regulation Of Histone H2A K63-linked Ubiquitination Negative Regulation Of Double-strand Break Repair	Placenta Development Apoptotic Process Animal Organ Morphogenesis Regulation Of Gene Expression Regulation Of Cell Migration Positive Regulation Of Apoptotic Process Regulation Of Embryonic Development Regulation Of Spongiotrophoblast Cell Proliferation Regulation Of Glycogen Metabolic Process Regulation Of Growth Hormone Activity
Pathways		Ovarian tumor domain proteases
Drugs
Diseases
GWAS			Calcium levels ( 20705733) Malaria ( 31844061)
Interacting Genes		42 interacting genes: APP ARRDC3 CDIP1 CPSF6 DAZAP2 FAM168A GLI2 KRT31 KRT40 LZTS2 MAGEA11 MID1 MID2 MKRN1 PHLDA2 PJA1 PLEKHB2 PMEPA1 RBCK1 REL RFFL RNF126 SIAH1 SPART TP53BP2 TRAF6 TRIM2 TRIM25 TRIM26 TRIM27 TRIM39 TRIM5 TRIM54 TRIM55 TRIM63 TRIM8 TRIP6 U2AF2 UBC UBE2N USP21 USP28	4 interacting genes: FCHO1 OTUB2 SSX2 SSX2B
Entrez ID		78990	7262
HPRD ID		07620	03679
Ensembl ID		ENSG00000089723	ENSG00000181649
Uniprot IDs		Q96DC9	Q53GA4
PDB IDs		1TFF 4FJV 5QIO 5QIP 5QIQ 5QIR 5QIS 5QIT 5QIU 5QIV 5QIW 5QIX 5QIY 5QIZ
Enriched GO Terms of Interacting Partners?
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