RNLS and MAST1

Data Source:
BioGRID (two hybrid)

		RNLS	MAST1
Description		renalase, FAD dependent amine oxidase	microtubule associated serine/threonine kinase 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Cytoplasm Cytoskeleton Plasma Membrane Axon Dendrite Neuron Projection Neuronal Cell Body
	Molecular Function	Protein Binding Oxidoreductase Activity, Acting On NAD(P)H Epinephrine Binding NADH Binding Monoamine Oxidase Activity	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Microtubule Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Response To Ischemia Negative Regulation Of Heart Rate NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway Negative Regulation Of Blood Pressure Response To Epinephrine Response To Salt	Protein Phosphorylation Cytoskeleton Organization Brain Development Peptidyl-serine Phosphorylation Intracellular Signal Transduction
Pathways		Nicotinamide salvaging
Drugs			Fostamatinib
Diseases
GWAS		Birth weight ( 31043758) Cortical amyloid beta load ( 29860282) Depressive and manic episodes in bipolar disorder ( 26297903) End stage renal disease in APOL1 risk genotype-negative individuals ( 29885931) Estimated glomerular filtration rate in coronary artery disease and impaired kidney function ( 30809046) Familial lung adenocarcinoma ( 29924316) Height ( 31562340) Hematocrit ( 32888494) Hemoglobin ( 32888494) Mercury levels ( 26025379) Prostate cancer ( 29892016) Pulse pressure ( 27841878) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Thyroid stimulating hormone levels ( 32769997) Type 1 diabetes ( 30659077 30572963) Youthful appearance (self-reported) ( 32339537)	High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) Intelligence (MTAG) ( 29326435) Mean corpuscular hemoglobin ( 29403010 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252) Red blood cell count ( 29403010) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		2 interacting genes: FAM107A MAST1	40 interacting genes: A2M AP1M2 APOE APP BLMH CDK5 CYP2C8 CYP2C9 DNAJB1 ECSIT EGFR ELAVL3 EXOC6 EXOSC1 FBXL12 FBXW4 GCDH HSP90AB1 IFIT3 IFIT5 LONP1 LOXL4 NOS3 OGA PAXIP1 PRAM1 PRDX2 PSEN2 PTEN RAB3A RAB3D RAD23A RNF32 RNLS RPP30 RPS6KA1 SNTA1 SNTB2 STAMBPL1 UBE2D3
Entrez ID		55328	22983
HPRD ID		07742	17469
Ensembl ID		ENSG00000184719	ENSG00000105613
Uniprot IDs		B4DJW3 Q5VYX0	Q9Y2H9
PDB IDs		3QJ4	2M9X 3PS4
Enriched GO Terms of Interacting Partners?
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