RNLS and FAM107A

Data Source:
BioGRID (two hybrid)

		RNLS	FAM107A
Description		renalase, FAD dependent amine oxidase	family with sequence similarity 107 member A
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Stress Fiber Nucleus Cytoplasm Focal Adhesion Actin Cytoskeleton Nuclear Speck Ruffle Membrane Neuron Projection Synapse
	Molecular Function	Protein Binding Oxidoreductase Activity, Acting On NAD(P)H Epinephrine Binding NADH Binding Monoamine Oxidase Activity	Molecular_function Actin Binding Protein Binding
	Biological Process	Response To Ischemia Negative Regulation Of Heart Rate NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway Negative Regulation Of Blood Pressure Response To Epinephrine Response To Salt	Regulation Of Cell Growth Cell Cycle Actin Filament Polymerization Positive Regulation Of Cell Migration Positive Regulation Of Protein Ubiquitination Regulation Of Protein Stability Cellular Response To Nutrient Levels Regulation Of Actin Cytoskeleton Organization Cognition Actin Filament Bundle Assembly Negative Regulation Of Focal Adhesion Assembly Regulation Of Microtubule Cytoskeleton Organization Cellular Response To Glucocorticoid Stimulus Negative Regulation Of Long-term Synaptic Potentiation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		Nicotinamide salvaging
Drugs
Diseases
GWAS		Birth weight ( 31043758) Cortical amyloid beta load ( 29860282) Depressive and manic episodes in bipolar disorder ( 26297903) End stage renal disease in APOL1 risk genotype-negative individuals ( 29885931) Estimated glomerular filtration rate in coronary artery disease and impaired kidney function ( 30809046) Familial lung adenocarcinoma ( 29924316) Height ( 31562340) Hematocrit ( 32888494) Hemoglobin ( 32888494) Mercury levels ( 26025379) Prostate cancer ( 29892016) Pulse pressure ( 27841878) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Thyroid stimulating hormone levels ( 32769997) Type 1 diabetes ( 30659077 30572963) Youthful appearance (self-reported) ( 32339537)	Blood protein levels ( 30072576) Night sleep phenotypes ( 27126917)
Interacting Genes		2 interacting genes: FAM107A MAST1	58 interacting genes: AGMAT APPBP2 AUH AZI2 BEGAIN BIRC8 CALCOCO2 CANX CCDC125 CCDC136 CCDC57 CCDC85B CPSF3 DAPK1 EFEMP2 EFHC2 EIF4A1 ESRRG FKBP6 FSD2 GFM2 GOLGA6L9 HFM1 HOOK2 HSF2BP HSPA14 HSPD1 HTRA1 IQUB ITPRID2 KRT15 KRT19 KRT27 KRT40 KRTAP4-12 LDOC1 LZTS2 MEIOB MID2 MTREX MTUS2 NEXN NFKBID NINL PLSCR1 PNMA1 POMP PSMD6 RAB18 RINT1 RNLS SPATA22 TADA2A TRAF2 TRIM37 USHBP1 VIM WDR47
Entrez ID		55328	11170
HPRD ID		07742	09753
Ensembl ID		ENSG00000184719	ENSG00000168309
Uniprot IDs		B4DJW3 Q5VYX0	A0A024R327 O95990 Q6IAM1
PDB IDs		3QJ4
Enriched GO Terms of Interacting Partners?
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