PFDN1 and HMGXB3

		PFDN1	HMGXB3
Description		prefoldin subunit 1	HMG-box containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Prefoldin Complex	Cellular_component Nucleus
	Molecular Function	Amyloid-beta Binding Protein Binding Protein Folding Chaperone Unfolded Protein Binding	DNA Binding
	Biological Process	Protein Folding Negative Regulation Of Amyloid Fibril Formation	Biological_process
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS		Alzheimer's disease ( 28183528) Alzheimer's disease in APOE e4- carriers ( 25778476) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Reaction time ( 29844566)	Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Monocyte percentage of white cells ( 32888494)
Interacting Genes		54 interacting genes: ACTA1 ACTB ALB BRK1 CCDC85A CEP126 CHGA DCTN1 DEFA1 DMAP1 EDRF1 EIF3C EIF4A2 EOMES ESS2 EXT2 EZH2 FAM20C GET3 GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 YEATS4 ZNF235	6 interacting genes: ANXA7 CDK4 CDKN1A PFDN1 SMN1 TK1
Entrez ID		5201	22993
HPRD ID		05357	19515
Ensembl ID		ENSG00000113068	ENSG00000113716
Uniprot IDs		O60925	Q12766 Q562E5
PDB IDs		6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
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