CISD2 and PLPPR2

Data Source:
BioGRID (two hybrid)

		CISD2	PLPPR2
Description		CDGSH iron sulfur domain 2	phospholipid phosphatase related 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Protein-containing Complex Perinuclear Endoplasmic Reticulum	Integral Component Of Plasma Membrane
	Molecular Function	RNA Binding Protein Binding Protein Homodimerization Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding	Protein Binding Phosphatidate Phosphatase Activity Lipid Phosphatase Activity
	Biological Process	Autophagy Of Mitochondrion Multicellular Organism Aging Regulation Of Autophagy	Phospholipid Metabolic Process Signal Transduction Phospholipid Dephosphorylation
Pathways			Lysosphingolipid and LPA receptors
Drugs
Diseases		Wolfram syndrome (WFS); DIDMOAD syndrome
GWAS		Asthma and attention deficit hyperactivity disorder ( 31619474) Estimated glomerular filtration rate ( 31152163) Primary biliary cholangitis ( 26394269) Schizophrenia ( 28991256) Type 2 diabetes ( 28869590)
Interacting Genes		58 interacting genes: AIG1 APOL2 APP AQP10 BCL2L2 BET1 BMP10 BTN2A2 C14orf180 C2CD2L C4orf3 CDIPT CFHR5 CLDN10 CLN6 CYBC1 EHHADH EMD FAM241B GALNT15 GAST GPR37L1 HHATL IER3 KIR2DL3 LEPROTL1 LRP10 MAN2B2 MIP NAPB NRG4 NSG1 PGAP2 PLPP4 PLPPR2 PNKP POMGNT1 RTP2 RUSF1 SEC22A SERP2 SLC13A3 SLC35B4 SMIM1 SNORC SPP1 STX12 STX7 THSD7B TMEM187 TMEM243 TMEM43 TMEM86A TSPAN33 TTPA VAMP4 VKORC1L1 YIPF6	21 interacting genes: ARL13B CD79A CIAO2A CISD2 CLDN5 CREB3L1 GYPC KIR2DL3 LYPD5 MARCHF2 SCN3B SIGLEC12 SLC19A3 SMAGP SSMEM1 STX12 TMED9 TMEM237 TMIE UBE2J1 VSIR
Entrez ID		493856	64748
HPRD ID		17413	17442
Ensembl ID		ENSG00000145354	ENSG00000105520
Uniprot IDs		Q8N5K1	A0A024R7E2 Q96GM1
PDB IDs		3FNV 4OO7 4OOA
Enriched GO Terms of Interacting Partners?
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