CISD2 and TSPAN33

Data Source:
BioGRID (two hybrid)

		CISD2	TSPAN33
Description		CDGSH iron sulfur domain 2	tetraspanin 33
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Protein-containing Complex Perinuclear Endoplasmic Reticulum	Endoplasmic Reticulum Lumen Plasma Membrane Integral Component Of Plasma Membrane Adherens Junction Cell Surface Pore Complex Tetraspanin-enriched Microdomain
	Molecular Function	RNA Binding Protein Binding Protein Homodimerization Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding	Protein Binding Enzyme Binding
	Biological Process	Autophagy Of Mitochondrion Multicellular Organism Aging Regulation Of Autophagy	Cellular Protein Metabolic Process Pore Complex Assembly Protein Maturation Protein Localization To Plasma Membrane
Pathways			Amyloid fiber formation
Drugs
Diseases		Wolfram syndrome (WFS); DIDMOAD syndrome
GWAS		Asthma and attention deficit hyperactivity disorder ( 31619474) Estimated glomerular filtration rate ( 31152163) Primary biliary cholangitis ( 26394269) Schizophrenia ( 28991256) Type 2 diabetes ( 28869590)	Estimated glomerular filtration rate ( 31015462) Ulcerative colitis ( 23128233)
Interacting Genes		58 interacting genes: AIG1 APOL2 APP AQP10 BCL2L2 BET1 BMP10 BTN2A2 C14orf180 C2CD2L C4orf3 CDIPT CFHR5 CLDN10 CLN6 CYBC1 EHHADH EMD FAM241B GALNT15 GAST GPR37L1 HHATL IER3 KIR2DL3 LEPROTL1 LRP10 MAN2B2 MIP NAPB NRG4 NSG1 PGAP2 PLPP4 PLPPR2 PNKP POMGNT1 RTP2 RUSF1 SEC22A SERP2 SLC13A3 SLC35B4 SMIM1 SNORC SPP1 STX12 STX7 THSD7B TMEM187 TMEM243 TMEM43 TMEM86A TSPAN33 TTPA VAMP4 VKORC1L1 YIPF6	27 interacting genes: CHRM2 CISD2 CLDN7 COQ9 DARS2 ERGIC3 FAM209A GAD2 GJA8 GORAB GPR152 GPX8 KCNK5 LHFPL5 LMNA MFF MGST3 MTIF3 NEMP1 PLEKHO1 RELL2 SHISA4 SIT1 SLC35C2 SPINT1 TMEM106C TMEM45B
Entrez ID		493856	340348
HPRD ID		17413	14669
Ensembl ID		ENSG00000145354	ENSG00000158457
Uniprot IDs		Q8N5K1	Q86UF1
PDB IDs		3FNV 4OO7 4OOA
Enriched GO Terms of Interacting Partners?
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