PLPPR2 and CLDN5

Data Source:
BioGRID (two hybrid)

		PLPPR2	CLDN5
Description		phospholipid phosphatase related 2	claudin 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Integral Component Of Membrane Apicolateral Plasma Membrane Cell Junction Cortical Actin Cytoskeleton Tight Junction
	Molecular Function	Protein Binding Phosphatidate Phosphatase Activity Lipid Phosphatase Activity	Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process	Phospholipid Metabolic Process Signal Transduction Phospholipid Dephosphorylation	Outflow Tract Morphogenesis Cell-cell Junction Assembly Cell Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Learning Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Negative Regulation Of Angiogenesis Negative Regulation Of Cell Migration Positive Regulation Of Protein Binding Maintenance Of Blood-brain Barrier Negative Regulation Of Vascular Permeability Roof Of Mouth Development Face Morphogenesis Bicellular Tight Junction Assembly Tight Junction Assembly Positive Regulation Of Establishment Of Endothelial Barrier Positive Regulation Of Bicellular Tight Junction Assembly Establishment Of Blood-retinal Barrier Regulation Of Bicellular Tight Junction Assembly
Pathways		Lysosphingolipid and LPA receptors	Tight junction interactions RUNX1 regulates expression of components of tight junctions
Drugs
Diseases
GWAS
Interacting Genes		21 interacting genes: ARL13B CD79A CIAO2A CISD2 CLDN5 CREB3L1 GYPC KIR2DL3 LYPD5 MARCHF2 SCN3B SIGLEC12 SLC19A3 SMAGP SSMEM1 STX12 TMED9 TMEM237 TMIE UBE2J1 VSIR	40 interacting genes: AQP1 BTNL8 CCDC167 CLDN3 CLRN2 CNPY3 CORIN CTRL CXCL9 CYB561A3 EFNA5 EHHADH ERG28 ERMP1 FXYD6-FXYD2 GYPA LAT LHFPL5 MIP MPDZ PLP2 PLPPR2 PMP22 RPRM SFTPC SGCG SLC35B4 SMIM3 TECR TF TJP1 TMEM128 TMEM140 TMEM14C TMEM182 TMEM190 TMEM222 TSPAN2 VAMP5 YIPF1
Entrez ID		64748	7122
HPRD ID		17442	03654
Ensembl ID		ENSG00000105520	ENSG00000184113
Uniprot IDs		A0A024R7E2 Q96GM1	D3DX19 O00501
PDB IDs
Enriched GO Terms of Interacting Partners?
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