CISD2 and HHATL

Data Source:
BioGRID (two hybrid)

		CISD2	HHATL
Description		CDGSH iron sulfur domain 2	hedgehog acyltransferase like
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Protein-containing Complex Perinuclear Endoplasmic Reticulum	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Protein Binding Protein Homodimerization Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding	Protein Binding Transferase Activity, Transferring Acyl Groups
	Biological Process	Autophagy Of Mitochondrion Multicellular Organism Aging Regulation Of Autophagy	Negative Regulation Of N-terminal Protein Palmitoylation
Pathways
Drugs
Diseases		Wolfram syndrome (WFS); DIDMOAD syndrome
GWAS		Asthma and attention deficit hyperactivity disorder ( 31619474) Estimated glomerular filtration rate ( 31152163) Primary biliary cholangitis ( 26394269) Schizophrenia ( 28991256) Type 2 diabetes ( 28869590)
Interacting Genes		58 interacting genes: AIG1 APOL2 APP AQP10 BCL2L2 BET1 BMP10 BTN2A2 C14orf180 C2CD2L C4orf3 CDIPT CFHR5 CLDN10 CLN6 CYBC1 EHHADH EMD FAM241B GALNT15 GAST GPR37L1 HHATL IER3 KIR2DL3 LEPROTL1 LRP10 MAN2B2 MIP NAPB NRG4 NSG1 PGAP2 PLPP4 PLPPR2 PNKP POMGNT1 RTP2 RUSF1 SEC22A SERP2 SLC13A3 SLC35B4 SMIM1 SNORC SPP1 STX12 STX7 THSD7B TMEM187 TMEM243 TMEM43 TMEM86A TSPAN33 TTPA VAMP4 VKORC1L1 YIPF6	20 interacting genes: ADRA1A AGTR1 AMIGO1 BDKRB1 C4orf3 CACNA1A CISD2 CPLX4 CXCL16 ERGIC3 FAM209A FKBP7 FNDC9 GPR152 GPX8 MILR1 MUC1 PVR SUSD3 TMX2
Entrez ID		493856	57467
HPRD ID		17413	12166
Ensembl ID		ENSG00000145354	ENSG00000010282
Uniprot IDs		Q8N5K1	A0A024R2R3 Q5QTR4 Q9HCP6
PDB IDs		3FNV 4OO7 4OOA
Enriched GO Terms of Interacting Partners?
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