CISD2 and C4orf3

Data Source:
BioGRID (two hybrid)

		CISD2	C4orf3
Description		CDGSH iron sulfur domain 2	chromosome 4 open reading frame 3
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Protein-containing Complex Perinuclear Endoplasmic Reticulum	Integral Component Of Membrane
	Molecular Function	RNA Binding Protein Binding Protein Homodimerization Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Autophagy Of Mitochondrion Multicellular Organism Aging Regulation Of Autophagy
Pathways
Drugs
Diseases		Wolfram syndrome (WFS); DIDMOAD syndrome
GWAS		Asthma and attention deficit hyperactivity disorder ( 31619474) Estimated glomerular filtration rate ( 31152163) Primary biliary cholangitis ( 26394269) Schizophrenia ( 28991256) Type 2 diabetes ( 28869590)	Blood protein levels ( 28240269)
Interacting Genes		58 interacting genes: AIG1 APOL2 APP AQP10 BCL2L2 BET1 BMP10 BTN2A2 C14orf180 C2CD2L C4orf3 CDIPT CFHR5 CLDN10 CLN6 CYBC1 EHHADH EMD FAM241B GALNT15 GAST GPR37L1 HHATL IER3 KIR2DL3 LEPROTL1 LRP10 MAN2B2 MIP NAPB NRG4 NSG1 PGAP2 PLPP4 PLPPR2 PNKP POMGNT1 RTP2 RUSF1 SEC22A SERP2 SLC13A3 SLC35B4 SMIM1 SNORC SPP1 STX12 STX7 THSD7B TMEM187 TMEM243 TMEM43 TMEM86A TSPAN33 TTPA VAMP4 VKORC1L1 YIPF6	67 interacting genes: ADGRG3 AQP2 AQP6 ARL13B BCL2L13 BIK C5AR2 CALM1 CCRL2 CD79A CISD2 CLDN9 CREB3L1 CXCR2 CYBC1 DEGS1 EBP ERGIC3 FAM174A FAM209A FFAR2 GJA5 GJB4 GJB5 GLP1R GPR61 HHATL HTR2C JAGN1 LAPTM5 LMNA LY6G6C MFSD14B MILR1 MMD MMGT1 MRM3 MS4A3 NCAPH2 PLEKHO1 PTGES REEP4 RETREG3 RHBDL1 RHCG SERINC2 SHISAL1 SLC14A2 SLC19A3 SLC35C2 SLC35E3 SLC39A2 SLC41A3 SLCO3A1 SMO SSMEM1 STX1A SYNPR TIMMDC1 TM4SF19 TMEM101 TMEM237 TMEM248 TMEM45A TMEM45B TMEM51 YIF1A
Entrez ID		493856	401152
HPRD ID		17413	14223
Ensembl ID		ENSG00000145354	ENSG00000164096
Uniprot IDs		Q8N5K1	Q8WVX3
PDB IDs		3FNV 4OO7 4OOA
Enriched GO Terms of Interacting Partners?
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