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PLPPR2 and VSIR
Data Source:
BioGRID
(two hybrid)
PLPPR2
VSIR
Description
phospholipid phosphatase related 2
V-set immunoregulatory receptor
Image
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Plasma Membrane
Plasma Membrane
Integral Component Of Membrane
Molecular Function
Protein Binding
Phosphatidate Phosphatase Activity
Lipid Phosphatase Activity
Protein Binding
Enzyme Binding
Identical Protein Binding
Endopeptidase Activator Activity
Biological Process
Phospholipid Metabolic Process
Signal Transduction
Phospholipid Dephosphorylation
Positive Regulation Of Gene Expression
Positive Regulation Of Endopeptidase Activity
Positive Regulation Of Cell Migration
Zymogen Activation
Negative Regulation Of Interferon-gamma Production
Negative Regulation Of Interleukin-10 Production
Negative Regulation Of Interleukin-17 Production
Negative Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Regulatory T Cell Differentiation
Regulation Of Immune Response
Positive Regulation Of Collagen Catabolic Process
Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation
Negative Regulation Of CD8-positive, Alpha-beta T Cell Proliferation
Pathways
Lysosphingolipid and LPA receptors
Drugs
Diseases
GWAS
Interacting Genes
21 interacting genes:
ARL13B
CD79A
CIAO2A
CISD2
CLDN5
CREB3L1
GYPC
KIR2DL3
LYPD5
MARCHF2
SCN3B
SIGLEC12
SLC19A3
SMAGP
SSMEM1
STX12
TMED9
TMEM237
TMIE
UBE2J1
VSIR
27 interacting genes:
APOD
ASGR1
ATP6V0C
BMP10
C14orf180
CCL4L2
CLEC7A
CLRN2
CNIH3
DOLK
MS4A13
PLPP6
PLPPR2
PLSCR1
SLC35B1
SLC35B4
SMAD3
SMCO4
TMEM100
TMEM14C
TMEM218
TMEM229B
TMEM97
TNF
TSPAN2
TSPO2
VAMP3
Entrez ID
64748
64115
HPRD ID
17442
15160
Ensembl ID
ENSG00000105520
ENSG00000107738
Uniprot IDs
A0A024R7E2
Q96GM1
Q9H7M9
PDB IDs
6MVL
6OIL
6U6V
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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