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KRT5 and KRT16
Data Source:
BioGRID
(biochemical, two hybrid)
KRT5
KRT16
Description
keratin 5
keratin 16
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Intermediate Filament
Membrane
Keratin Filament
Extracellular Exosome
Nucleus
Cytosol
Cytoskeleton
Intermediate Filament
Extracellular Exosome
Molecular Function
Structural Constituent Of Cytoskeleton
Protein Binding
Scaffold Protein Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Biological Process
Cytoskeleton Organization
Epidermis Development
Keratinization
Hemidesmosome Assembly
Cornification
Morphogenesis Of An Epithelium
Inflammatory Response
Cytoskeleton Organization
Aging
Keratinocyte Differentiation
Negative Regulation Of Cell Migration
Keratinization
Hair Cycle
Innate Immune Response
Intermediate Filament Cytoskeleton Organization
Keratinocyte Migration
Establishment Of Skin Barrier
Cornification
Pathways
Type I hemidesmosome assembly
Keratinization
Formation of the cornified envelope
Keratinization
Formation of the cornified envelope
Drugs
Zinc
Zinc acetate
Zinc
Zinc acetate
Diseases
Dowling-Degos disease
Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
Non-epidermolytic palmoplantar keratoderma (NEPPK)
Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS
Basal cell carcinoma (
31174203
24403052
25855136
27539887
)
Cutaneous squamous cell carcinoma (
32041948
)
Keratinocyte cancer (MTAG) (
31174203
)
Non-melanoma skin cancer (
29739929
)
Squamous cell carcinoma (
31174203
)
Interacting Genes
25 interacting genes:
ALOX12
ALOX12B
APC
DSP
DST
EVPL
INCA1
KIFC3
KRT1
KRT14
KRT15
KRT16
KRT18
KRT19
KRT24
KRT25
KRT27
KRT28
KRT31
KRT35
KRT38
KRT40
PKP2
TCHP
UBE3A
56 interacting genes:
AMOT
ARFIP2
C1orf109
C1orf216
CARD9
CCDC146
CCDC17
CCHCR1
CCNC
CDK18
CYTH4
EPM2AIP1
GAS8
GNG10
HGS
KIFC3
KLC4
KRT1
KRT2
KRT3
KRT4
KRT5
KRT6A
KRT6C
KRT71
KRT72
KRT73
KRT74
KRT76
KRT78
KRT79
KRT8
KRT80
KRT81
KRT83
KRT85
KRT86
LMO1
LNX1
MBD3
PKN1
POLL
PPP1R18
PRKAA2
PRPH
PUS10
SEMA4C
SGF29
SMARCD1
SMARCE1
SNAPIN
TCHP
TSG101
TTC23
TXLNB
USHBP1
Entrez ID
3852
3868
HPRD ID
01010
01018
Ensembl ID
ENSG00000186081
ENSG00000186832
Uniprot IDs
P13647
P08779
PDB IDs
3TNU
6JFV
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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