KRT5

Description		keratin 5
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Intermediate Filament Membrane Keratin Filament Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Scaffold Protein Binding
	Biological Process	Cytoskeleton Organization Epidermis Development Keratinization Hemidesmosome Assembly Cornification
Pathways		Type I hemidesmosome assembly Keratinization Formation of the cornified envelope
Drugs		Zinc Zinc acetate
Diseases		Dowling-Degos disease Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
GWAS		Basal cell carcinoma ( 31174203 24403052 25855136 27539887) Cutaneous squamous cell carcinoma ( 32041948) Keratinocyte cancer (MTAG) ( 31174203) Non-melanoma skin cancer ( 29739929) Squamous cell carcinoma ( 31174203)
Novel Interacting Genes		10 novel interacting genes: DCTN1 GPD1 KRT4 KRT6A KRT6B KRT7 NADSYN1 SAP18 SORD TARBP2
Interacting Genes		25 interacting genes: ALOX12 ALOX12B APC DSP DST EVPL INCA1 KIFC3 KRT1 KRT14 KRT15 KRT16 KRT18 KRT19 KRT24 KRT25 KRT27 KRT28 KRT31 KRT35 KRT38 KRT40 PKP2 TCHP UBE3A
Entrez ID		3852
HPRD ID		01010
Ensembl ID		ENSG00000186081
Uniprot IDs		P13647
PDB IDs		3TNU 6JFV
Enriched GO Terms of Interacting Partners?
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