KRT16 and PRPH

Data Source:
BioGRID (two hybrid)

		KRT16	PRPH
Description		keratin 16	peripherin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Intermediate Filament Extracellular Exosome	Cytoplasm Intermediate Filament Membrane Axon Perikaryon Type III Intermediate Filament Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding	Structural Molecule Activity Protein Binding
	Biological Process	Morphogenesis Of An Epithelium Inflammatory Response Cytoskeleton Organization Aging Keratinocyte Differentiation Negative Regulation Of Cell Migration Keratinization Hair Cycle Innate Immune Response Intermediate Filament Cytoskeleton Organization Keratinocyte Migration Establishment Of Skin Barrier Cornification	Intermediate Filament Cytoskeleton Organization
Pathways		Keratinization Formation of the cornified envelope
Drugs		Zinc Zinc acetate
Diseases		Non-epidermolytic palmoplantar keratoderma (NEPPK) Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex	Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
GWAS			Prostate cancer ( 21743467) Sural nerve amplitude potential ( 30992453)
Interacting Genes		56 interacting genes: AMOT ARFIP2 C1orf109 C1orf216 CARD9 CCDC146 CCDC17 CCHCR1 CCNC CDK18 CYTH4 EPM2AIP1 GAS8 GNG10 HGS KIFC3 KLC4 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6C KRT71 KRT72 KRT73 KRT74 KRT76 KRT78 KRT79 KRT8 KRT80 KRT81 KRT83 KRT85 KRT86 LMO1 LNX1 MBD3 PKN1 POLL PPP1R18 PRKAA2 PRPH PUS10 SEMA4C SGF29 SMARCD1 SMARCE1 SNAPIN TCHP TSG101 TTC23 TXLNB USHBP1	36 interacting genes: CDC37 CT55 DDX6 DES FCHO1 INCA1 KIFC3 KRT14 KRT15 KRT16 KRT19 KRT20 KRT24 KRT27 KRT31 KRT75 LCA5L LENG1 LMNB1 LNX1 MAGOHB MYO5A NXF1 PIAS2 PPP1R13B PPP1R18 PRKAA2 PRPH2 PSMA1 TCEA2 TCP10L TTC23 VIM ZC4H2 ZMAT2 ZNF572
Entrez ID		3868	5630
HPRD ID		01018	01365
Ensembl ID		ENSG00000186832	ENSG00000135406
Uniprot IDs		P08779	B3KWQ6 P41219
PDB IDs
Enriched GO Terms of Interacting Partners?
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