KRT16 and KRT72

Data Source:
BioGRID (two hybrid)

		KRT16	KRT72
Description		keratin 16	keratin 72
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Intermediate Filament Extracellular Exosome	Cytosol Keratin Filament Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding	Molecular_function Protein Binding
	Biological Process	Morphogenesis Of An Epithelium Inflammatory Response Cytoskeleton Organization Aging Keratinocyte Differentiation Negative Regulation Of Cell Migration Keratinization Hair Cycle Innate Immune Response Intermediate Filament Cytoskeleton Organization Keratinocyte Migration Establishment Of Skin Barrier Cornification	Biological_process Keratinization Cornification
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs		Zinc Zinc acetate
Diseases		Non-epidermolytic palmoplantar keratoderma (NEPPK) Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS			High density lipoprotein cholesterol levels ( 30498476)
Interacting Genes		56 interacting genes: AMOT ARFIP2 C1orf109 C1orf216 CARD9 CCDC146 CCDC17 CCHCR1 CCNC CDK18 CYTH4 EPM2AIP1 GAS8 GNG10 HGS KIFC3 KLC4 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6C KRT71 KRT72 KRT73 KRT74 KRT76 KRT78 KRT79 KRT8 KRT80 KRT81 KRT83 KRT85 KRT86 LMO1 LNX1 MBD3 PKN1 POLL PPP1R18 PRKAA2 PRPH PUS10 SEMA4C SGF29 SMARCD1 SMARCE1 SNAPIN TCHP TSG101 TTC23 TXLNB USHBP1	19 interacting genes: BLOC1S6 HSPB1 KRT13 KRT14 KRT15 KRT16 KRT17 KRT18 KRT19 KRT20 KRT24 KRT25 KRT27 KRT31 KRT32 KRT33B KRT35 KRT38 KRT40
Entrez ID		3868	140807
HPRD ID		01018	09746
Ensembl ID		ENSG00000186832	ENSG00000170486
Uniprot IDs		P08779	Q14CN4
PDB IDs
Enriched GO Terms of Interacting Partners?
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