MRC2 and PPM1D

Number of citations of the paper that reports this interaction (PubMedID 25640309)
5

Data Source:
BioGRID (two hybrid)

		MRC2	PPM1D
Description		mannose receptor C type 2	protein phosphatase, Mg2+/Mn2+ dependent 1D
Image			No pdb structure
GO Annotations	Cellular Component	Focal Adhesion Membrane Integral Component Of Membrane	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding Collagen Binding Carbohydrate Binding Signaling Receptor Activity	Protein Serine/threonine Kinase Activity Protein Serine/threonine Phosphatase Activity Magnesium-dependent Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding Mitogen-activated Protein Kinase Binding
	Biological Process	Osteoblast Differentiation Endocytosis Collagen Catabolic Process	G2/M Transition Of Mitotic Cell Cycle DNA Methylation Chromatin Silencing Transcription Initiation From RNA Polymerase II Promoter Protein Phosphorylation Protein Dephosphorylation Negative Regulation Of Cell Proliferation Cellular Response To Starvation Response To Radiation Response To Bacterium DNA Damage Response, Signal Transduction By P53 Class Mediator Peptidyl-threonine Dephosphorylation Negative Regulation Of Gene Expression, Epigenetic
Pathways		Cross-presentation of soluble exogenous antigens (endosomes) Cross-presentation of soluble exogenous antigens (endosomes)	Transcriptional regulation by RUNX2
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) Diastolic blood pressure ( 28135244 30578418) Heel bone mineral density ( 30598549) Pulse pressure ( 28135244 30578418) Systolic blood pressure ( 30578418)	Blood urea nitrogen levels ( 31152163)
Interacting Genes		13 interacting genes: AKT1 BAG4 BRMS1 ESR2 MTDH NDEL1 PALB2 PAX2 PPM1D PTPN1 RAF1 RB1CC1 XRCC3	25 interacting genes: ATP6V1A BEX2 CASZ1 CHEK2 DIRAS3 DKK3 EPSTI1 ERRFI1 GLCE H3-3A H3C1 ITIH5 KDM1A LYPD3 MAPK11 MDM2 MRC2 NAT2 NCL NSD3 OSGIN1 RHOBTB2 RPL5 TP53 UBC
Entrez ID		9902	8493
HPRD ID		10094	05482
Ensembl ID		ENSG00000011028	ENSG00000170836
Uniprot IDs		Q9UBG0	A0A0S2Z4M2 O15297
PDB IDs		5AO5 5AO6 5E4K 5E4L 5EW6
Enriched GO Terms of Interacting Partners?
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