PPM1D and DIRAS3

Number of citations of the paper that reports this interaction (PubMedID 25640309)
5

Data Source:
BioGRID (two hybrid)

		PPM1D	DIRAS3
Description		protein phosphatase, Mg2+/Mn2+ dependent 1D	DIRAS family GTPase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Plasma Membrane
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine Phosphatase Activity Magnesium-dependent Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding Mitogen-activated Protein Kinase Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle DNA Methylation Chromatin Silencing Transcription Initiation From RNA Polymerase II Promoter Protein Phosphorylation Protein Dephosphorylation Negative Regulation Of Cell Proliferation Cellular Response To Starvation Response To Radiation Response To Bacterium DNA Damage Response, Signal Transduction By P53 Class Mediator Peptidyl-threonine Dephosphorylation Negative Regulation Of Gene Expression, Epigenetic	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Gene Expression By Genetic Imprinting Small GTPase Mediated Signal Transduction
Pathways		Transcriptional regulation by RUNX2
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163)
Interacting Genes		25 interacting genes: ATP6V1A BEX2 CASZ1 CHEK2 DIRAS3 DKK3 EPSTI1 ERRFI1 GLCE H3-3A H3C1 ITIH5 KDM1A LYPD3 MAPK11 MDM2 MRC2 NAT2 NCL NSD3 OSGIN1 RHOBTB2 RPL5 TP53 UBC	12 interacting genes: ACADM APC BAG4 BRMS1 CHEK2 FGFR4 KRAS PALB2 PPM1D PTPN1 TGFB1 WT1
Entrez ID		8493	9077
HPRD ID		05482	05547
Ensembl ID		ENSG00000170836	ENSG00000162595
Uniprot IDs		A0A0S2Z4M2 O15297	O95661
PDB IDs
Enriched GO Terms of Interacting Partners?
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