MRC2 and RB1CC1

Number of citations of the paper that reports this interaction (PubMedID 25640309)
5

Data Source:
BioGRID (two hybrid)

		MRC2	RB1CC1
Description		mannose receptor C type 2	RB1 inducible coiled-coil 1
Image
GO Annotations	Cellular Component	Focal Adhesion Membrane Integral Component Of Membrane	Phagophore Assembly Site Lysosome Endoplasmic Reticulum Membrane Cytosol Extrinsic Component Of Membrane Nuclear Membrane Phagophore Assembly Site Membrane Atg1/ULK1 Kinase Complex
	Molecular Function	Protein Binding Collagen Binding Carbohydrate Binding Signaling Receptor Activity	Protein Binding Protein Kinase Binding Molecular Adaptor Activity
	Biological Process	Osteoblast Differentiation Endocytosis Collagen Catabolic Process	Autophagosome Assembly Autophagy Of Mitochondrion Liver Development Positive Regulation Of Protein Phosphorylation Autophagy Cell Cycle Heart Development Macroautophagy Regulation Of Macroautophagy Autophagy Of Peroxisome Piecemeal Microautophagy Of The Nucleus Positive Regulation Of Cell Size Positive Regulation Of JNK Cascade Reticulophagy Glycophagy Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Cross-presentation of soluble exogenous antigens (endosomes) Cross-presentation of soluble exogenous antigens (endosomes)	Macroautophagy
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) Diastolic blood pressure ( 28135244 30578418) Heel bone mineral density ( 30598549) Pulse pressure ( 28135244 30578418) Systolic blood pressure ( 30578418)	Immunoglobulin light chain (AL) amyloidosis (liver involvement) ( 28679651) Mitochondrial DNA copy number (white blood cells) ( 30704525) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		13 interacting genes: AKT1 BAG4 BRMS1 ESR2 MTDH NDEL1 PALB2 PAX2 PPM1D PTPN1 RAF1 RB1CC1 XRCC3	36 interacting genes: ATG13 BAP1 BLID CALCOCO2 COP1 EPSTI1 ERRFI1 EXOC1 GABARAP GABARAPL1 GABARAPL2 GLCE GREB1 HBP1 IL13RA2 IL24 ITIH5 LYPD3 MADD MAP1LC3A MAP1LC3B MAP1LC3C MRC2 NSD3 PSMC3IP PTK2 PTK2B RNF20 SYN1 TBKBP1 THRSP UBC UMPS VHL VPS45 WIF1
Entrez ID		9902	9821
HPRD ID		10094	06019
Ensembl ID		ENSG00000011028	ENSG00000023287
Uniprot IDs		Q9UBG0	Q8TDY2
PDB IDs		5AO5 5AO6 5E4K 5E4L 5EW6	6DCE 6GMA
Enriched GO Terms of Interacting Partners?
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