PPM1D and OSGIN1

Number of citations of the paper that reports this interaction (PubMedID 25640309)
5

Data Source:
BioGRID (two hybrid)

		PPM1D	OSGIN1
Description		protein phosphatase, Mg2+/Mn2+ dependent 1D	oxidative stress induced growth inhibitor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Cellular_component
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine Phosphatase Activity Magnesium-dependent Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding Mitogen-activated Protein Kinase Binding	Protein Binding Growth Factor Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle DNA Methylation Chromatin Silencing Transcription Initiation From RNA Polymerase II Promoter Protein Phosphorylation Protein Dephosphorylation Negative Regulation Of Cell Proliferation Cellular Response To Starvation Response To Radiation Response To Bacterium DNA Damage Response, Signal Transduction By P53 Class Mediator Peptidyl-threonine Dephosphorylation Negative Regulation Of Gene Expression, Epigenetic	Signal Transduction Multicellular Organism Development Cell Differentiation Negative Regulation Of Cell Growth Regulation Of Cell Migration Regulation Of Cell Proliferation Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process
Pathways		Transcriptional regulation by RUNX2
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163)	LDL cholesterol ( 30275531) Pursuit maintenance gain ( 29064472) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
Interacting Genes		25 interacting genes: ATP6V1A BEX2 CASZ1 CHEK2 DIRAS3 DKK3 EPSTI1 ERRFI1 GLCE H3-3A H3C1 ITIH5 KDM1A LYPD3 MAPK11 MDM2 MRC2 NAT2 NCL NSD3 OSGIN1 RHOBTB2 RPL5 TP53 UBC	23 interacting genes: AKT1 ATM BCAR3 CAPN3 CCDC33 CRX DNAJA3 FGFR4 IKZF3 INCA1 KRAS LNX1 MEIS2 MEOX2 PPM1D PTEN REL SAXO1 SMARCB1 TCF12 TCF4 TLE5 XRCC3
Entrez ID		8493	29948
HPRD ID		05482	06412
Ensembl ID		ENSG00000170836	ENSG00000140961
Uniprot IDs		A0A0S2Z4M2 O15297	Q9UJX0
PDB IDs
Enriched GO Terms of Interacting Partners?
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